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Search results for 'AG 490'
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PhiKan 083
PhiKan 083 is a p53 stabilizing agent that binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protein interaction regions. Learn MoreStarting at: $125.00
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NSC 146109 hydrochloride
NSC 146109 hydrochloride is cell-permeable, genotype-selective antitumor agent that increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Learn MoreStarting at: $109.00
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Melphalan
Melphalan is a DNA alkylating agent; induces cytotoxicity through the formation of stable interstrand and intrastrand crosslinks within DNA which inhibits growth of PC-3 cells (IC50 values are 0.074 and 0.77 μM for sequential dosing and single dosing respectively). Learn MoreStarting at: $65.00
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CP 31398 dihydrochloride
CP 31398 dihydrochloride is a p53 stabilizing agent, which stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53 and inhibits growth of small human tumor xenografts in vivo. Learn MoreStarting at: $90.00
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RETRA hydrochloride
RETRA hydrochloride is an antitumor agent, that inhibits tumor cell growth in a mutant p53- and p73-dependent manner in vitro and in vivo (IC50 = 4 μM). Learn MoreStarting at: $95.00
