Search results for 'PI 103'
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MDL 28170
MDL 28170 is a potent, selective inhibitor of calpain and cathepsin B that rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo. Learn MoreStarting at: $65.00
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SCH 202676 hydrobromide
SCH 202676 hydrobromide is a sulphydryl-reactive compound that inhibits agonist and antagonist binding to G-protein-coupled receptors that inhibits a variety of GPCRs including adenosine, opioid, muscarinic, adrenergic and dopaminergic receptors IC50 values of 0.1-1.8 μM. Learn MoreStarting at: $115.00
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HPI 1
HPI 1, a Hedgehog (Hh) signaling inhibitor, inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells with IC50 values of 1.5, 1.5, 4 and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced activation. Learn MoreStarting at: $129.00
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Bropirimine
Bropirimine, an Immunomodulatory and antitumor compound, induces interferon (IFN)-α/β production and augments natural killer (NK) cell activity. Orally active. Learn MoreStarting at: $93.00
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Pirfenidone
Pirfenidone is a antifibrotic agent, effective in models of pulmonary and lung fibrosis that regulates cytokine levels following oral administration in vivo. Learn MoreStarting at: $89.00
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DMPO
Water soluble nitric oxide spin trap; allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin resonance (ESR). Learn MoreStarting at: $55.00
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Ciliobrevin A
Ciliobrevin A is a hedgehog (Hh) pathway antagonist which blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo. Learn MoreStarting at: $119.00
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Gallein
Gallein is an inhibitor of G protein βγ subunit-dependent signaling, which blocks PI 3-kinase and Rac1 activation in HL60 cells and chemotaxis in HL60 differentiated cells. Learn MoreStarting at: $55.00
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D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt
D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt, as an important second messenger involved in Ca2+ mobilization from intracellular stores (EC50 = 0.1 μM), is formed from the enzymatic hydrolysis of phosphatidyl inositol-4,5-bisphosphate. . Learn MoreStarting at: $119.00
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DHBP dibromide
DHBP dibromide is a blocks calcium release from sarcoplasmic reticulum by direct interaction with the ryanodine receptor. Learn MoreStarting at: $55.00