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Search results for 'CT 47098'
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BTZO 1
BTZO 1 is a macrophage migration inhibitory factor (MIF) binder (Kd = 68.6 nM), which activates antioxidant response element (ARE)-mediated gene expression and suppresses oxidative stress-induced cardiomyocyte apoptosis in vitro. Learn MoreStarting at: $95.00
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SD 1008
SD 1008 is a JAK2/STAT3 signaling pathway inhibitor, which inhibits activation of STAT3, JAK2 and Src. Learn MoreStarting at: $109.00
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BI 6015
BI 6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that exhibits cytotoxic activity in a range of tumor cell lines, including human hepatocellular carcinoma. Learn MoreStarting at: $129.00
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W-13 hydrochloride
W-13 hydrochloride is a calmodulin antagonist that inhibits calmodulin activated PDE activity with an IC50 of 68 μM. Learn MoreStarting at: $99.00
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CCG 50014
CCG 50014 is a potent and selective inhibitor of regulator of G-protein signaling 4 (RGS4) protein that exhibits >20-fold selectivity for RGS4 over other RGS proteins. Learn MoreStarting at: $125.00
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MDL 28170
MDL 28170 is a potent, selective inhibitor of calpain and cathepsin B that rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo. Learn MoreStarting at: $65.00
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AM 114
AM 114 is an inhibitor of the chymotrypsin-like activity of the 20S proteasome that inhibits cell growth in human colon cancer HCT116 p53+/+ cells. Learn MoreStarting at: $99.00
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ICG 001
ICG 001 is an inhibitor of TCF/β-catenin-mediated transcription that inhibits β-catenin/CBP interaction. Learn MoreStarting at: $99.00
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ML 130
ML 130 is a potent and selective inhibitor of NOD1 that inhibits NOD1-induced NF-κB activation in HEK293 cells with no cytotoxicity. Learn MoreStarting at: $119.00
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A-7 hydrochloride
A-7 hydrochloride is a potent calmodulin antagonist that inhibits calmodulin-activated PDE activity with an IC50 of 3 μM. Learn MoreStarting at: $89.00
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8-Bromo-cAMP (sodium salt)
8-Bromo-cAMP(sodium salt) is a cell-permeable cAMP analog and activator of protein kinase A. Learn MoreStarting at: $59.00
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CID 2858522
CID 2858522 selectively inhibits protein kinase C (PKC)-induced activation of the NF-κB pathway and inhibits antigen receptor-stimulated NF-κB activation in chronic lymphocytic leukemia (CLL) B cells. Learn MoreStarting at: $109.00
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CID 5951923
CID 5951923 is an inhibitor of Krüppel-like factor 5 (KLF5) transcription factor. Learn MoreStarting at: $149.00
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Carbenoxolone disodium
Carbenoxolone disodium is a glucocorticoid that inhibits 11β-hydroxysteroid dehydrogenase (11-HSD) and blocks gap junction communication. Learn MoreStarting at: $65.00
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Macbecin I
Macbecin I is an ensamycin antibiotic compound that inhibits Hsp90 activity by binding to the ATP-binding site. Learn MoreStarting at: $199.00
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cAMPS-Rp, triethylammonium salt
cAMPS-Rp, triethylammonium salt is a cell-permeable cAMP analog that acts as a competitive antagonist of cAMP-induced activation of PKA by interacting with cAMP binding sites on the regulatory subunits. Learn MoreStarting at: $99.00
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cAMPS-Sp, triethylammonium salt
cAMPS-Sp, triethylammonium salt is a cell-permeable cAMP analog that activates cAMP receptor proteins such as PKA and cAMP-regulated guanine nucleotide exchange factor. Learn MoreStarting at: $99.00
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SCH 202676 hydrobromide
SCH 202676 hydrobromide is a sulphydryl-reactive compound that inhibits agonist and antagonist binding to G-protein-coupled receptors that inhibits a variety of GPCRs including adenosine, opioid, muscarinic, adrenergic and dopaminergic receptors IC50 values of 0.1-1.8 μM. Learn MoreStarting at: $115.00
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W-9 hydrochloride
W-9 hydrochloride is a Calmodulin antagonist that inhibits calmodulin-activated PDE activity with an IC50 of 72 μM. Learn MoreStarting at: $109.00
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iCRT 14
iCRT 14 is a potent inhibitor of β-catenin-responsive transcription (CRT) with IC50 of 40.3 nM in assays of Wnt pathway activity. Learn MoreStarting at: $139.00
