Search results for 'CT'
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ARP 101
ARP 101 is a selective inhibitor of MMP-2 that displays ~ 600-fold selectivity over MMP-1. Learn MoreStarting at: $115.00
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ARP 100
ARP 100 is a selective inhibitor of MMP-2 (IC50 = 12 nM) with selectivity over MMP-9, MMP-3, MMP-1 and MMP-7. Learn MoreStarting at: $99.00
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H 1152 dihydrochloride
H 1152 dihydrochloride is a rho-kinase (ROCK) inhibitor that displays high selectivity over other protein kinases (IC50 values are 0.012, 0.180, 0.360, 0.745, 3.03, 5.68 and 28.3 μM for ROCKII, CAMKII, PKG, Aurora A, PKA, PKC and MLCK respectively). Learn MoreStarting at: $139.00
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WAY 170523
WAY 170523 is a potent and selective inhibitor of MMP-13 (IC50 values are 17, 945, > 1000 and > 10000 nM for MMP-13, MMP-9, TACE and MMP-1 respectively). Learn MoreStarting at: $79.00
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GI 254023X
GI 254023X is a selective ADAM10 metalloprotease inhibitor; displays over 100-fold higher potency at ADAM10 compared to ADAM17. Learn MoreStarting at: $119.00
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KF 38789
KF 38789 is a selective inhibitor of P-selectin-mediated cell adhesion (IC50 = 1.97 μM) that displays no effects on L-selectin- and E-selectin-mediated adhesion. Learn MoreStarting at: $135.00
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Doxycycline hyclate
Doxycycline hyclate is a broad-spectrum antibiotic and MMP inhibitor; tetracycline derivative. Learn MoreStarting at: $80.00
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UK 370106
UK 370106 is a highly selective MMP-3 and MMP-12 inhibitor (IC50 values are 0.023, 0.042, 1.75, 2.3, 5.8, 30.4, 34.2 and 66.9 μM at MMP 3, 12, 8, 13, 7, 9, 2 and 14 respectively.) Learn MoreStarting at: $155.00
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UK 356618
UK 356618 is a potent and selective inhibitor of MMP-3 (IC50 = 5.9 nM), which displays selectivity over a range of MMPs (IC50 values are 73, 840, 1790, 1900 and 51000 for MMP-13, MMP-9, MMP-2, MMP-14 and MMP-1 respectively). Learn MoreStarting at: $189.00
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ONO 4817
ONO 4817 is a broad spectrum MMP inhibitor; Ki values are 0.45, 0.73, 1.1, 1.1, 2.1, 42 and 2500 nM for MMP-12, MMP-2, MMP-8, MMP-13, MMP-9, MMP-3 and MMP-7 respectively and IC50 = 1600 nM for MMP-1). It exhibits antiangiogenic and anti-invasive properties on lung metastasis of murine renal cell carcinoma. Learn MoreStarting at: $189.00
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CP 471474
CP 471474 is a broad spectrum MMP inhibitor (IC50 values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively). Learn MoreStarting at: $95.00
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PD 166793
PD 166793 is a broad spectrum MMP inhibitor. Displays high affinity for MMP-2, -3 and -13 (IC50 values are 4, 7 and 8 nM respectively) and exhibits > 750-fold selectivity over MMP-1, -7 and -9. Attenuates left ventricular remodelling and dysfunction in rat model of heart failure. Learn MoreStarting at: $90.00
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Ro 32-3555
Ro 32-3555 is a potent, collagenase-selective MMP inhibitor (Ki values are 3.0, 3.4, 4.4, 59, 154 and 527 nM for MMP-1, MMP-13, MMP-8, MMP-9, MMP-2 and MMP-3 respectively) which inhibits cartilage breakdown in vitro and in vivo and displays antiarthritic activity. Learn MoreStarting at: $175.00
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Y-27632 dihydrochloride
Y-27632 dihydrochloride is a selective inhibitor of the Rho-associated protein kinase p160ROCK. Ki values are 0.14, 26, 25 and > 250 μM for p160ROCK, PKC, cAMP-dependent protein kinase and myosin light-chain kinase respectively. Learn MoreStarting at: $60.00
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HA 1100 hydrochloride
HA 1100 hydrochlorid is a cell-permeable active metabolite of Fasudil, which also inhibits neutrophil migration and produces potent vasodilatory effects in vivo. Learn MoreStarting at: $135.00