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Angiogenesis
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AG 555
AG 555 is a potent epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.7 μM) that displays 50-fold and >140-fold selectivity over ErbB2 and insulin receptor kinase respectively. Learn MoreStarting at: $80.00
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AG 494
AG 494 is a potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.7 μM). Learn MoreStarting at: $85.00
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Tyrphostin B44, (+) enantiomer
Tyrphostin B44, (+) enantiomer is an epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.86 μM). Learn MoreStarting at: $105.00
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AG 556
Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 1.1 μM) and selective over ErbB2 (IC50 > 500 μM). Learn MoreStarting at: $80.00
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AG 825
AG 825 is a selective ErbB2 inhibitor (IC50 values are 0.15 and 19 μM at ErbB2 and ErbB1 respectively). Learn MoreStarting at: $90.00
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PD 158780
PD 158780 is a potent inhibitor of ErbB receptor family tyrosine kinases (IC50 values are 0.008, 49 and 52 nM for EGFR, ErbB2 and ErbB2/ErbB4 respectively), which induces G1 cell cycle arrest in MCF10A cells and is antiproliferative in A431 human epidermal carcinoma cells. Learn MoreStarting at: $135.00
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GW 583340 dihydrochloride
GW 583340 dihydrochloride is a potent dual EGFR/ErbB2 tyrosine kinase inhibitor (IC50 values are 0.01 and 0.014 μM respectively), which selectively inhibits growth of human tumor cells overexpressing EGFR and ErbB2 (IC50 values are 0.11 μM for inhibition of HN5, N87 and BT474 tumor cell lines vs. > 30 μM for inhibition of non-tumor cell line HFF). Learn MoreStarting at: $139.00
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Methyl 2,5-dihydroxycinnamate
Methyl 2,5-dihydroxycinnamate is an inhibitor of EGF receptor-associated tyrosine kinases. Learn MoreStarting at: $81.00
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AG 18
AG 18 is an inhibitor of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase (IC50 values are 35 and 25 μM respectively, whichi inhibits EGF-stimulated cell proliferation. Also acts as a mitochondrial uncoupler that alters phosphorylation-dependent cell signaling. Learn MoreStarting at: $80.00
