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Signal Transduction
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AM 114
AM 114 is an inhibitor of the chymotrypsin-like activity of the 20S proteasome that inhibits cell growth in human colon cancer HCT116 p53+/+ cells. Learn MoreStarting at: $99.00
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Eeyarestatin I
Eeyarestatin I is a potent inhibitor of endoplasmic reticulum associated protein degradation (ERAD), which specifically targets the p97-associated deubiquinating process (PAD) and inhibits ataxin-3 (atx3)-dependent deubiquitination. Learn MoreStarting at: $149.00
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Exo1
Exo1 is a reversible inhibitor of vesicular trafficking between endoplasmic reticulum and Golgi apparatus. Learn MoreStarting at: $95.00
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Leptomycin B
Leptomycin B, an antifungal antibiotic, is an inhibitor of the nuclear export of proteins that inhibits the nuclear export of the HIV regulatory protein Rev and stabilizes p53. Learn MoreStarting at: $239.00
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NDT 9513727
NDT 9513727 is a potent C5a receptor (C5aR) competitive antagonist (IC50 = 11.6 nM); selective for human C5aR (IC50 values for rat and mouse C5aR are > 10 μM), which exhibits inverse agonist pharmacokinetics. Learn MoreStarting at: $189.00
