You have no items in your shopping cart.
Protein Kinase C
-
Rottlerin
Rottlerin is riginally reported to inhibit PKC isoforms, inhibit CAM kinase III, and inhibit a wide range of protein kinases. Learn MoreStarting at: $69.00
-
C-1
C-1 is an inhibitor of protein kinase C. Learn MoreStarting at: $105.00
-
Oncrasin 1
Oncrasin 1 is a proapoptotic agent that exhibits antiproliferative effects against various human tumor cell lines with K-Ras mutations (IC50 ≤ 3 μM) with minimal effects on normal epithelial cells and inhibits human xenograft growth by 75% in vivo. Learn MoreStarting at: $105.00
-
(±)-Palmitoylcarnitine chloride
(±)-Palmitoylcarnitine chloride has a wide range of biological actions including the inhibition of protein kinase C and cell membrane disruption. Learn MoreStarting at: $89.00
-
LY 333531 hydrochloride
Ras CAAX peptidomimetic, a selective inhibitor of farnesyltransferase (FTase) that displays > 100-fold selectivity over geranylgeranyltransferase I (GGTase I) (IC50 values are 0.5 and 50 nM respectively). Learn MoreStarting at: $110.00
-
Phorbol 12-myristate 13-acetate
Naltrexone hydrochloride is an opioid antagonist. Learn MoreStarting at: $50.00
-
Phorbol 12,13-dibutyrate
Phorbol 12,13-dibutyrate is a protein kinase C activator, which induces contraction of vascular smooth muscle and inhibits MLC phosphatase (MLCP) in vascular smooth muscle. Learn MoreStarting at: $55.00
-
Chelerythrine chloride
Chelerythrine chloride is a cell-permeable inhibitor of protein kinase C (IC50 = 660 nM); competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. Learn MoreStarting at: $95.00
-
Dihydrosphingosine
Dihydrosphingosine is a protein kinase C inhibitor. Learn MoreStarting at: $99.00
-
FR 236924
FR 236924 is a selective PKCε activator that displays > 7-fold selectivity over other PKC isozymes. Learn MoreStarting at: $119.00
-
Ro 32-0432 hydrochloride
Ro 32-0432 hydrochloride is a selective cell-permeable protein kinase C inhibitor, which displays slight selectivity for conventional PKC isoforms over Ca2+ and atypical PKC isoforms; binding affinities for rat isoforms are 9, 28, 31, 37 and 108 nM for PKC's α, βΙ, βΙΙ, γ and ε respectively. Learn MoreStarting at: $140.00
-
CGP 53353
CGP 53353 is a selective inhibitor of PKCβII (IC50 values are 0.41 and 3.8 μM for PKCβII and PKCβI respectively), which inhibits prionogenic Sup35 fibrillization (IC50 ~ 3.4 μM) and inhibits de novo Aβ42 assembly in vitro. Learn MoreStarting at: $155.00
-
Bisindolylmaleimide II
Bisindolylmaleimide II is a potent, ATP-competitive protein kinase C (PKC) inhibitor (IC50 = 0.01 μM) which displays selectivity for PKC over protein kinase A (PKA) and phosphorylase kinase (PK) (IC50 values are 0.75 and 2μM for PK and PKA respectively). Learn MoreStarting at: $135.00
-
D-erythro-Sphingosine (synthetic)
D-erythro-Sphingosine (synthetic) is an inhibitor of protein kinase C and calmodulin-dependent enzymes, but may stimulate mast cells by activation of protein kinase C. Learn MoreStarting at: $65.00
-
Calphostin C
Calphostin C is a potent, selective and photo-dependent inhibitor of protein kinase C that targets the regulatory domain (IC50 = 50 nM). Learn MoreStarting at: $165.00
-
SC-10
SC-10 is a activator of protein kinase C. Learn MoreStarting at: $95.00
-
SC-9
SC-9 is a potent activator of protein kinase C. Learn MoreStarting at: $95.00
-
K-252c
K-252c is an inhibitor of protein kinase C that exhibits antiviral activity against GCV-sensitive and -resistant strains of human cytomegalovirus (HCMV). Learn MoreStarting at: $99.00
