PF 3644022

PF 3644022 is a potent, ATP-competitive inhibitor of mitogen-activated protein kinase (MAPK)-activated protein kinase-2 (MK2) (IC50 = 5.2 nM; Ki = 3 nM) which inhibits tumor necrosis factor α (TNFα) production in U937 monocytic cells and peripheral blood mononuclear cells (PBMCs) (IC50 = 160 nM).

Availability: In stock

Product Name Price Qty
PF 3644022 10mg
$180.00

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Additional Info
Additional Info
Catalog No. ES1497
CAS Number 1276121-88-0
Formula C21H18N4OS
M. Wt 374.46
Purity >98 %
Solubility Soluble to 100 mM in DMSO
Chemical Name (10R)-9,10,11,12-Tetrahydro-10-meth​yl-3-(6-methyl-3-pyridinyl)-8H-[1,4]diazepino[5',6':​4,5]thieno[3,2-f]quinolin-8-one
Synonyms N/A
Storage Store at +4°C
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