Peptide Receptors
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L-692,585
L-692,585 is a highly potent, non-peptide ghrelin receptor (GHS-R1a) agonist (Ki = 0.8 nM) which increases plasma GH levels in vivo and is 2- to 2.5-fold more potent than GHRP-6. Learn MoreStarting at: $185.00
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Tabimorelin hemifumarate
Tabimorelin hemifumarate is a potent, orally active ghrelin receptor (GHS-R1a) agonist (Ki = 50 nM at human recombinant GHS-R1a), which induces hyperphagia and adiposity in lean rats, but not in leptin signaling-deficient ZDF rats. Learn MoreStarting at: $229.00
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WAY 207024 dihydrochloride
WAY 207024 dihydrochloride is a gonadotropin releasing hormone receptor (GnRH-R) antagonist that exhibits potent affinity with IC50 values of 12 and 71 nM for human and rat GnRH receptors respectively. Learn MoreStarting at: $189.00
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AG 045572
AG 045572 is a selective gonadotropin-releasing hormone (GnRH) receptor antagonist (Ki values are 2.2, 3.8 and 6.0 nM for mouse, rat and human receptors respectively). Learn MoreStarting at: $79.00
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T 98475
T 98475 is a potent, orally active and non-peptide gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist (IC50 values are 0.2, 4.0 and 60 nM for human, monkey and rat GnRH receptors respectively) which inhibits LH release in vitro (IC50 = 100 nM) and reduces plasma LH concentration in castrated male cynomolgus monkeys. Learn MoreStarting at: $145.00
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SNAP 94847 hydrochloride
SNAP 94847 hydrochloride is a potent melanin-concentrating hormone receptor 1 (MCH1) antagonist (Ki = 2.2 nM, KD = 530 pM) that displays > 80-fold and > 500-fold selectivity over α1A and D2 receptors respectively. Learn MoreStarting at: $149.00
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ATC 0065
ATC 0065 is an orally active, potent and selective melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 = 15.7 nM) that displays > 96-fold selectivity over MCH2. Learn MoreStarting at: $149.00
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ATC 0175 hydrochloride
ATC 0175 hydrochloride is a potent, selective and orally active melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 values are 13.5 and > 10000 nM for MCH1 and MCH2 receptors respectively). Learn MoreStarting at: $149.00
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GW 803430
GW 803430 is an orally active melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 = 9.3 nM) with antiobesity and antidepressant-like effects in rats and mice.. Learn MoreStarting at: $150.00
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TC-MCH 7c
TC-MCH 7c is a potent, selective melanin-concentrating hormone receptor 1 (MCH1R) antagonist. Learn MoreStarting at: $195.00
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BMS 470539 dihydrochloride
BMS 470539 dihydrochlorideis a potent, selective melanocortin MC1 receptor agonist (IC50 = 120 nM), which exhibits anti-inflammatory properties following ischemia-reperfusion in the vasculature. Learn MoreStarting at: $169.00
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RF 9
RF 9 is a selective NPFF receptor antagonist that blocks NPFF-induced hypothermia and increases in atrial blood pressure and heart rate, and prevents opioid-induced tolerance associated with hyperalgesia in vivo. Learn MoreStarting at: $85.00
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SR 142948
SR 142948 is a potent non-peptide neurotensin (NT) receptor antagonist that binds with high affinity (IC50 = 0.32 - 3.96 nM; Ki < 10 nM). Learn MoreStarting at: $85.00
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L-152804
L-152804 is a potent, selective non-peptide neuropeptide Y Y5 receptor antagonist with > 300-fold selectivity over hY1, hY2, and hY4 receptors. Learn MoreStarting at: $145.00
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BIBP 3226 trifluoroacetate
3F8 is a potent and selective GSK-3β inhibitor (IC50 values are 34 and 304 nM in the presence of 10 and 100 μM ATP respectively). Learn MoreStarting at: $90.00
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NTNCB hydrochloride
NTNCB hydrochloride is a selective, non-peptide competitive NPY Y5 antagonist. Ki values are 8.0 and 16032 nM at human recombinant Y5 and Y1 receptors respectively. Learn MoreStarting at: $149.00
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SF 11
SF 11 is a NPY Y2 antagonist (IC50 = 199 nM), which displays no affinity for Y1 receptor at concentrations up to 35 μM. Causes significant lethality in mice. Brain penetrant. Learn MoreStarting at: $139.00
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NPY 5RA972
NPY 5RA972 is a potent and selective neuropeptide Y Y5 receptor antagonist (IC50 values are 3.1, >10000, >10000 and >10000 nM for Y5, Y1, Y2 and Y4 receptors respectively). Does not block NPY-induced feeding in vivo. Orally active and brain penetrant. Learn MoreStarting at: $135.00
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LU AA33810
LU AA33810 is a potent neuropeptide Y (NPY) Y5 receptor antagonist (Ki = 1.5 nM in vitro) which displays ≥ 3300-fold affinity for Y5 over Y1, Y2 and Y4 receptors. Learn MoreStarting at: $109.00
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S 25585
S 25585 is a potent neuropeptide Y (NPY) Y5 receptor antagonist (IC50 values are 5.4, > 1000, > 10 000 and > 10 000 nM at Y5, Y1, Y2 and Y4 receptors respectively) that displays no affinity for a wide range of other receptors. Learn MoreStarting at: $139.00