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Ro 8-4304 hydrochloride
Ro 8-4304 hydrochloride is a NMDA receptor antagonist (IC50 = 0.4 μM) that displays > 100 fold selectivity for NR2B-containing receptors over NR2A-containing receptors, which exhibits an activity-dependent mechanism of NMDA antagonism and is competitive with respect to spermine.
Additional Info
Additional Info
| Catalog No. | ES2180 |
|---|---|
| CAS Number | 195988-65-9 |
| Formula | C21H23FN2O3.HCl |
| M. Wt | 406.88 |
| Purity | >98 % |
| Solubility | Soluble to 10 mM in water and to 100 mM in DMSO |
| Chemical Name | 4-[3-[4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1(2H)-pyridinyl]-2-hydroxypropoxy]benzamide hydrochloride |
| Synonyms | N/A |
| Storage | Desiccate at RT |
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