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IκB Kinase
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IKK 16
IKK 16 is a selective inhibitor of IκB kinase (IKK) (IC50 values are 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively), which inhibits TNF-α-stimulated IκB degradation and LPS-induced TNF-α release in vivo and neutrophil extravasion in thioglycollate-induced peritonitis. Learn MoreStarting at: $125.00
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PF 184
PF 184 is a Potent and selective IKKβ inhibitor (IC50 = 37 nM), which displays selectivity over 85 other kinases and inhibits IL-1β-induced TNF-α production in a steroid-insensitive in vitro model of oxidative stress. Learn MoreStarting at: $195.00
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ACHP
ACHP is a IκB kinase inhibitor (IC50 values are 8.5 and 250 nM for IKKβ and IKKα respectively), which inhibits DNA binding activity of NF-κB. Blocks NF-κB pathway in multiple myeloma cell lines; induces cell growth arrest and apoptosis. Learn MoreStarting at: $209.00
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Amlexanox
Amlexanox is a selective inhibitor of TANK-binding kinase 1 (TBK1) and IKKε. Learn MoreStarting at: $63.00
