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Hsp90
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CCT 018159
CCT 018159 is a novel inhibitor of heat shock protein 90 (Hsp90) ATPase activity (IC50 = 5.7 μM) that displays selectivity over human Hsp72 and topoisomerase II. Learn MoreStarting at: $98.00
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Gedunin
Gedunin naturally occurring Hsp90 inhibitor, which induces Hsp90-dependent client protein degradation and displays antiproliferative activity in vitro (IC50 values are 3.22, 8.84 and 16.8 μM in SKBr3, MCF-7 and CaCo-2 cancer cell lines respectively). Learn MoreStarting at: $139.00
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17-DMAG hydrochloride
17-DMAG hydrochloride is a water-soluble analog of 17-AAG and geldanamycin, which binds the ATP binding site of Hsp90 and inhibits its chaperone activity, and displays more potent antitumor activity than 17-AAG (mean GI50 values are 53 and 123 nM for 17-DMAG and 17-AAG respectively). Learn MoreStarting at: $159.00
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Macbecin I
Macbecin I is an ensamycin antibiotic compound that inhibits Hsp90 activity by binding to the ATP-binding site. Learn MoreStarting at: $199.00
