T 98475

T 98475 is a potent, orally active and non-peptide gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist (IC50 values are 0.2, 4.0 and 60 nM for human, monkey and rat GnRH receptors respectively) which inhibits LH release in vitro (IC50 = 100 nM) and reduces plasma LH concentration in castrated male cynomolgus monkeys.

Availability: In stock

Product Name Price Qty
T 98475 1mg
$145.00

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Additional Info
Additional Info
Catalog No. ES2157
CAS Number 192887-28-8
Formula C37H37F2N3O4S
M. Wt 657.77
Purity >98 %
Solubility Soluble to 50 mM in DMSO
Chemical Name 7-[(2,6-Difluorophenyl)methyl]-4,7-​dihydro-2-[4-[(2-methyl-1-oxopropyl)amino]phenyl]-​3-[[methyl(phenylmethyl)amino]methyl]-4-oxo-thieno​[2,3-b]pyridine-5-carboxylic acid 1-methylethyl ester
Synonyms T98475
Storage Desiccate at +4°C
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