Glutamate (Metabotropic) Receptors

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  • DCG IV

    DCG IV is a presynaptic depressant; highly potent agonist for group II mGlu receptors. Learn More

    Starting at: $135.00

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  • EGLU

    EGLU is a selective antagonist of presynaptically-mediated (1S,3S)-ACPD-induced depression of motoneuron excitation in neonatal rat spinal cord; presumed group II mGlu receptor antagonist. Learn More

    Starting at: $110.00

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  • Ro 64-5229

    Ro 64-5229 is a selective, non-competitive mGlu2 antagonist which inhibits GTPγ35S binding to mGlu2-containing membranes (IC50 = 0.11 μM). Learn More

    Starting at: $140.00

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  • Spaglumic acid

    Spaglumic acid is the most abundant peptide neurotransmitter in the mammalian CNS. Learn More

    Starting at: $109.00

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  • LY 487379 hydrochloride

    LY 487379 hydrochloride is a positive allosteric modulator selective for mGlu2 receptors, which potentiates glutamate-stimulated [35S]GTPγS binding (EC50 values are 1.7 and > 10 μM for mGlu2 and mGlu3 receptors respectively). Learn More

    Starting at: $110.00

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  • MAP4

    (S)-SNAP 5114 is a GABA transport inhibitor, showing selectivity for GAT-3 and GAT-2 (IC50 values are 5, 21 and 388 μM for hGAT-3, rGAT-2 and hGAT-1 respectively). Learn More

    Starting at: $135.00

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  • ACPT-II

    ACPT-II is a competitive metabotropic receptor antagonist (KB values are 115, 88 and 77 μM at mGlu1a, mGlu2 and mGlu4a respectively). Learn More

    Starting at: $140.00

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  • L-Glutamic acid

    L-Glutamic is the predominant excitatory transmitter in the mammalian central nervous system. It acts at ionotropic and metabotropic glutamate receptors. Learn More

    Starting at: $32.00

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