γ-Secretase

Compound W

Compound W is an inhibitor of γ-secretase; causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). Learn More

Starting at: $55.00

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L-685,458

L-685,458 is a potent and selective γ-secretase inhibitor (IC50 = 17 nM) that displays > 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. Learn More

Starting at: $189.00

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JLK 6

JLK 6 is inhibitor of γ-secretase that selectively inhibits βAPP cleavage without affecting other γ-secretase-mediated pathways. Learn More

Starting at: $109.00

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MRK 560

MRK 560 inhibits proteolytic cleavage of amyloid precursor protein (APP) over the Notch pathway. Learn More

Starting at: $149.00

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