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L-655,708
L-655,708 is a potent, selective inverse agonist for the benzodiazepine site of GABAA receptors containing the α5 subunit (Ki = 0.45 nM), which displays 50-100-fold selectivity over GABAA receptors containing α1, α2, α3 or α6 subunits in combination with β3 and γ2.
Additional Info
Additional Info
| Catalog No. | ES1536 |
|---|---|
| CAS Number | 130477-52-0 |
| Formula | C18H19N3O4 |
| M. Wt | 341.37 |
| Purity | >98 % |
| Solubility | Soluble to 5 mM in DMSO and to 10 mM in 1eq. HCl with gentle warming |
| Chemical Name | 11,12,13,13a-Tetrahydro-7-methoxy-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid, ethyl ester |
| Synonyms | N/A |
| Storage | Desiccate at +4°C |
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