GABA Receptors
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Ganaxolone
Ganaxolone is a potent positive allosteric modulator of GABAA receptors, which enhances GABA-evoked chloride currents in Xenopus oocytes expressing GABAA receptors (EC50 values are 94, 122 and 213 nM for α2β1γ2L, α3β1γ2L and α1β1γ2L receptors respectively). Learn MoreStarting at: $99.00
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CGP 13501
CGP 13501 is a positive allosteric modulator of GABAB receptors that potentiates the effects of GABA at this receptor type. Learn MoreStarting at: $99.00
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Etifoxine hydrochloride
Etifoxine hydrochloride is a potentiator of GABAA receptor function in cultured neurons that preferentially acts on β2 or β3 subunit-containing GABAA receptors. Learn MoreStarting at: $109.00
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Phenobarbital sodium salt
Phenobarbital sodium salt enhances GABAergic activity. Learn MoreStarting at: $38.00
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Pentobarbital sodium salt
Pentobarbital sodium salt can enhance GABAergic activity. Learn MoreStarting at: $38.00
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CGP 7930
CGP 7930 acts as a positive allosteric modulator of GABAB receptors that enhances the inhibitory effect of the agonist L-baclofen in cultured cortical neurons and increases the potency and efficacy of GABA at both native and recombinant GABAB receptors with EC50 values of 5.37 and 4.60μM respectively. Learn MoreStarting at: $89.00
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Midazolam hydrochloride
Midazolam hydrochloride is a Sedative/hypnotic agent that acts at the GABAA receptor benzodiazepine modulatory site. Learn MoreStarting at: $129.00
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Vigabatrin
Vigabatrin is a selective GABA-T (transaminase) inhibitor. Learn MoreStarting at: $71.00
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TP 003
TP 003 is a selective GABAA receptor (α3 subtype) partial agonist that exhibits affinity for the benzodiazepine binding site on human GABAA receptors and potentiates the GABA (α3 subtype) response selectively with high efficacy. Learn MoreStarting at: $139.00
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Pentylenetetrazole
Pentylenetetrazole is a CNS stimulant that induces kindling in vivo. Learn MoreStarting at: $45.00
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(-)-Bicuculline methochloride
(-)-Bicuculline methochloride is a methochloride salt of (+)-bicuculline. Learn MoreStarting at: $85.00
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GS 39783
GS 39783 is a novel positive allosteric modulator of GABAB receptor function. Potentiates the effects of GABA on [35S]GTPγS binding at recombinant and native GABAB receptors (EC50 values are 2.1 and 3.1μM respectively). Learn MoreStarting at: $109.00
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(-)-Bicuculline methiodide
(-)-Bicuculline methiodide is a methiodide form of classical GABAA receptor antagonist (+)-bicuculline. Learn MoreStarting at: $79.00
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Tracazolate hydrochloride
Tracazolate hydrochloride is a subtype-selective GABAA receptor modulator, which can potentiate or inhibit recombinant GABAA function depending on subunit combination. Learn MoreStarting at: $75.00
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SB 205384
A selective, competitive and orally active GABAB antagonist which displays an IC50 of 1.1 μM at GABAB, approximately 60 times that of CGP 35348 and no binding affinity for GABAA at concentrations up to 100 μM. Learn MoreStarting at: $135.00
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SCH 50911
BW 723C86 hydrochloride is a selective 5-HT2B receptor agonist. Learn MoreStarting at: $155.00
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Flunitrazepam
Melperone hydrochloride is atypical neuroleptic; 5-HT2A/D2 receptor antagonist (Ki values are 120 and 180 nM respectively). Learn MoreStarting at: $75.00
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Allopregnanolone
Allopregnanolone is GABAA receptor positive allosteric modulator. Learn More -
Chlormethiazole hydrochloride
Chlormethiazole hydrochloride, a sedative and anticonvulsant, prevents the degeneration of serotonergic nerve terminals induced by MDMA ('Ecstasy'). Learn MoreStarting at: $91.00
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Isoguvacine hydrochloride
Isoguvacine hydrochloride is a specific GABAA receptor agonist that suppresses low magnesium induced seizure like events in organotypic hippocampal brain slices. Learn MoreStarting at: $146.00