You have no items in your shopping cart.
Enzymes
-
TC-F 2
TC-F 2 is a potent, reversible inhibitor of fatty acid amide hydrolase (FAAH) (IC50 values are 28 and 100 nM for human and rat FAAH respectively), which displays selectivity for FAAH over cannabinoid-related targets (IC50 > 20 μM for CB1, CB2 and TRPV1). Learn MoreStarting at: $155.00
-
PD 198306
PD 198306 is a potent inhibitor of MEK1/2, which inhibits isolated enzyme at a concentration of 8 nM and inhibits MEK activity in synovial fibroblasts at concentrations of 30 - 100 nM. Learn MoreStarting at: $189.00
-
NS 2028
NS 2028 is a potent soluble guanylyl cyclase (sGC) inhibitor (Ki = 8 nM), which inhibits VEGF-induced cGMP accumulation; abolishes VEGF-induced migration in postcapillary venular endothelial cells (CVEC). Learn MoreStarting at: $139.00
-
C 75
C 75 is a synthetic inhibitor of fatty acid synthase (FAS) which inhibits fatty acid synthesis in vitro and in vivo and displays anorectic effects. Induces apoptosis in MCF-7 xenografts and exhibits anti-tumor activity. Learn MoreStarting at: $135.00
-
Mithramycin A
Mithramycin A is an anticancer antibiotic that selectively binds to G-C-rich DNA in the presence of Mg2+ or Zn2+, inhibiting RNA and DNA polymerase action. Learn MoreStarting at: $75.00
-
TAME hydrochloride
TAME hydrochloride is a competitive inhibitor of the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C); promotes Cdc20 autoubiquitination. Learn MoreStarting at: $39.00
-
L-690,330
L-690,330 is a potent inhibitor of inositol monophophatase; stable to hydrolysis. Induces autophagy in COS-7 cells independently of mTOR inhibition. Learn MoreStarting at: $110.00
-
L-690,488
L-690,488 is a cell-permeable prodrug of the potent inositol monophosphatase inhibitor L-690,330; Learn MoreStarting at: $185.00
-
N-Acetyl-L-leucyl-L-leucyl-L-methional
N-Acetyl-L-leucyl-L-leucyl-L-methional is a very potent inhibitor of cathepsin L (Ki = 0.6 nM) and the strongest inhibitor of cathepsin B (Ki = 100 nM) amongst the peptide aldehydes. Learn MoreStarting at: $90.00
-
D-myo-Inositol-1,3,4,5-tetrakisphosphate, octapotassium salt
D-myo-Inositol-1,3,4,5-tetrakisphosphate, octapotassium salt is a phosphorylation product of inositol 1,4,5-trisphosphate (Ins (1,4,5)P3). Learn MoreStarting at: $135.00
-
SA 57
SA 57 is a potent inhibitor of fatty acid amide hydrolase (FAAH) (IC50 < 10 nM), which inhibits both human and mouse FAAH enzymes and displays inhibitory activity against FAAH, MAGL and ABHD6 in vivo. Learn MoreStarting at: $100.00
-
TCS JNK 6o
TCS JNK 6o is an ATP-competitive c-Jun N-terminal kinase (JNK) inhibitor that inhibits c-Jun phosphorylation (EC50 = 920 nM) and prevents collagen-induced platelet aggregation in vitro. Learn MoreStarting at: $149.00
-
3-Bromo-7-nitroindazole
3-Bromo-7-nitroindazole is a potent inhibitor of rat cerebellar nitric oxide synthase that is more potent than 7-nitroindazole. Learn MoreStarting at: $89.00
-
AEG 3482
AEG 3482 is an inhibitor of c-jun N-terminal kinase (JNK) signaling that binds Hsp90 and facilitates HSF1 release, induces expression of Hsp70, which in turn blocks JNK activation and JNK-dependent apoptosis. Learn MoreStarting at: $89.00
-
SU 3327
SU 3327 is a selective inhibitor of c-Jun N-terminal kinase (JNK) (IC50 = 0.7 μM), which inhibits the protein-protein interaction between JNK and JIP (IC50 = 239 nM). Learn MoreStarting at: $115.00
-
Anisomycin
Anisomycin is a protein synthesis inhibitor (blocks translation), which acts as a potent signaling agonist to selectively elicit homologous desensitization of immediate early gene induction (c-fos, fosB, c-jun, junB and junD). Learn MoreStarting at: $65.00
-
ARL 17477 dihydrochloride
ARL 17477 dihydrochloride is a selective neuronal nitrogen oxide synthase (nNOS) inhibitor (IC50 values are 1 and 17 μM for nNOS and endothelial NOS respectively). Learn MoreStarting at: $95.00
-
Nω-Propyl-L-arginine hydrochloride
Nω-Propyl-L-arginine hydrochloride is a highly selective and potent inhibitor of nNOS (Ki = 57 nM) which displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Learn MoreStarting at: $120.00
-
TMPyP4 tosylate
Cationic porphyrin; inhibits human telomerase. Stacks with G tetrads to stabilize quadruplex DNA, which inhibits cell proliferation and induces cell death in three myeloma cell lines. Learn MoreStarting at: $79.00
-
SC 57461A
SC 57461A is a potent and selective inhibitor of LTA4 hydrolase, which potently inhibits LTB4 production in whole blood (IC50 = 49 nM). Learn MoreStarting at: $99.00
