Reductases
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EBPC
EBPC is a potent aldose reductase inhibitor, which improves the cytotoxicity of anticancer reagents such as cisplatin and doxorubicin in HeLa cervical carcinoma cells through an increase in ERK activity. Learn MoreStarting at: $89.00
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Alrestatin
Alrestatin is a specific inhibitor of aldose reductase (IC50 = 148 μM). Learn MoreStarting at: $90.00
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CI 898 trihydrochloride
CI 898 trihydrochloride is a potent lipophilic inhibitor of dihydrofolate reductase (DHFR) that inhibits protozoal, bacterial and human DHFR with IC50 values of 1.4, 6.1 and 3.2 nM respectively. Learn MoreStarting at: $139.00
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ES 936
ES 936 is a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase (NQO1), which inhibits TNF-α-induced E-selectin protein expression in human bone marrow endothelial cells. Learn MoreStarting at: $140.00
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PMX 464
PMX 464 is a putative inhibitor of the thioredoxin-thioredoxin reductase (Trx-TrxR) system, which shown to inhibit Trx and induce a G1/S block in HT29 cells, and inhibits cell proliferation in various colorectal cancer cell lines and MCF7 cells. Learn MoreStarting at: $109.00