Search results for 'AP 24534'

8 Item(s)

per page

  • AT 101

    AT101, a natural product from cottonseed with a BH3-mimetic structure, was identified as a small molecule inhibitor of Bcl-2/Bcl-xL/Mcl-1 that potently induces apoptosis in various cancer cell lines. Learn More

    Starting at: $105.00

    View Details

  • Ivachtin

    Ivachtin is a potent, reversible inhibitor of caspase-3 that exhibits antiapoptotic activity in human Jurkat T cells treated with staurosporine and also a higher level of protection than Z-VAD-FMK. Learn More

    Starting at: $85.00

    View Details

  • MIRA-1

    MIRA-1 is a Restores wild-type conformation, function and DNA binding activity to mutant p53 that induces p53 transcriptional transactivation of p21, MDM2 and PUMA, and promotes tumor cell death by apoptosis in a mutant p53-dependent manner in vitro (IC50 = 10μM). Learn More

    Starting at: $89.00

    View Details

  • Chloroquine diphosphate

    Chloroquine diphosphate is an antimalarial drug, which inhibits cell growth and induces cell death in numerous cancer cell lines; inhibits cell proliferation and viability and induces apoptosis in 4T1 mouse breast cancer cells in vitro. Learn More

    Starting at: $59.00

    View Details

  • SJ 172550

    SJ 172550 is a MDMX inhibitor, which reversibly binds MDMX (EC50 = 2.3 μM), and inhibits the MDMX-p53 interaction in cultured retinoblastoma cells; frees p53 to induce apoptosis. Learn More

    Starting at: $119.00

    View Details

  • 2,3-DCPE hydrochloride

    2,3-DCPE hydrochloride selectively induces apoptosis and downregulates Bcl-XL protein expression in various human cancer cells versus normal cells in vitro. IC50 values are 0.89 and 12.6 μM for LoVo human colon cancer cell line and normal human fibroblasts respectively. Learn More

    Starting at: $75.00

    View Details

  • iMAC2

    iMAC2 is an inhibitor of mitochondrial apoptosis-induced channel (MAC) (IC50 = 28 nM), which reduces STS-induced apoptosis in FL5.12 cells by over 50% and inhibits release of cytochrome c by Bid-induced Bax activation (IC50 = 0.68 μM). Learn More

    Starting at: $149.00

    View Details

  • CHM 1

    CHM 1 is an inducer of apoptosis; displays potent antitumor ability in human hepatocellular carcinoma which inhibits tubulin polymerization in vitro and in vivo. Causes cell cycle arrest at G2/M phase by activation of Cdc2 kinase activity. Learn More

    Starting at: $100.00

    View Details

8 Item(s)

per page