You have no items in your shopping cart.
Search results for 'hp'
-
Starting at: $800.00
-
Starting at: $800.00
-
Starting at: $800.00
-
Starting at: $800.00
-
UCL 2077
UCL 2077 is a slow afterhyperpolarization (sAHP) channel blocker that reduces sAHP in hippocampal slice preparations. Learn MoreStarting at: $105.00
-
MRS 2693 trisodium salt
MRS 2693 trisodium salt is a selective P2Y6 agonist with an EC50 value of 0.015 μM at the hP2Y6 receptor. Learn MoreStarting at: $179.00
-
(S)-4-Carboxy-3-hydroxyphenylglycine
(S)-4-Carboxy-3-hydroxyphenylglycine is a competitive antagonist at group I mGlu1a/1a receptors, mixed effect at mGlu5a/5b receptors. Learn MoreStarting at: $265.00
-
HPI 1
HPI 1, a Hedgehog (Hh) signaling inhibitor, inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells with IC50 values of 1.5, 1.5, 4 and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced activation. Learn MoreStarting at: $129.00
-
NSC 87877
NSC 87877 is a potent inhibitor of shp2 and shp1 protein tyrosine phosphatases (PTP). NSC 87877 blocks epidermal growth factor receptor-induced activation of Ras and ERK1/2 in HEK293 cells, stimulates store-operated calcium entry in response to thrombin in platelets, and increased acetylcholine receptor clustering in myotubes. Learn MoreStarting at: $95.00
-
(S)-3-Carboxy-4-hydroxyphenylglycine
(S)-3-Carboxy-4-hydroxyphenylglycine is a mixed group I metabotropic glutamate receptor antagonist and group II mGlu agonist. Learn MoreStarting at: $269.00
-
Allopregnanolone
Allopregnanolone is GABAA receptor positive allosteric modulator. Learn More -
CHPG
E4CPG is a novel group I/group II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG. Learn MoreStarting at: $80.00
-
SC 236
CHPG is a selective mGlu5 metabotropic glutamate receptor agonist, completely inactive at mGlu1a receptors expressed in CHO cells. Learn MoreStarting at: $110.00
-
(S)-3,5-DHPG
BYK 49187 is a PARP-1 and PARP-2 inhibitor (pIC50 values are 8.36 and 7.50 for cell-free recombinant PARP-1 and murine PARP-2 respectively) which displays potent inhibitory activity against human PARP-1 in cell-free and cellular assays in vitro. Learn MoreStarting at: $95.00
-
CDP 840 hydrochloride
(S)-3,5-DHPG is a selective group I mGlu receptor agonist. Learn MoreStarting at: $135.00
-
ACHP
ACHP is a IκB kinase inhibitor (IC50 values are 8.5 and 250 nM for IKKβ and IKKα respectively), which inhibits DNA binding activity of NF-κB. Blocks NF-κB pathway in multiple myeloma cell lines; induces cell growth arrest and apoptosis. Learn MoreStarting at: $209.00
-
2-ThioUTP tetrasodium salt
2-ThioUTP tetrasodium salt is a potent and selective P2Y2 agonist (EC50 values are 0.035, 0.35 and 1.5 μM for hP2Y2, hP2Y4 and hP2Y6 receptors respectively). Learn MoreStarting at: $269.00
-
Ciliobrevin A
Ciliobrevin A is a hedgehog (Hh) pathway antagonist which blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo. Learn MoreStarting at: $119.00
-
TCS 401
TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) (Ki values are 0.29, 59, 560, 1100, > 2000, > 2000 and > 2000 μM for PTP1B, CD45 D1D2, PTPβ, PTPε D1, SHP-1, PTPα D1 and LAR D1D2 respectively). Learn MoreStarting at: $139.00
-
AZ 11645373
AZ 11645373 is a potent and selective human P2X7 antagonist (KB values are 5 - 7 and > 10,000 nM at hP2X7 and rP2X7 respectively) that is completely without effect at all other P2X subtypes. Learn MoreStarting at: $140.00
