Wnt Signaling

7 Item(s)

per page

  • exo-IWR 1

    exo-IWR 1 is negative control for endo-IWR 1. It also exhibits decreased activity against the Wnt/β-catenin pathway. Learn More

    Starting at: $90.00

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  • PNU 74654

    PNU 74654 Binds to β-catenin (KD = 450 nM) and inhibits the interaction between β-catenin and T cell factor 4 (Tcf4) and disrupts the Wnt signaling pathway. Learn More

    Starting at: $90.00

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  • CCT 031374 hydrobromide

    CCT 031374 hydrobromide is an inhibitor of TCF-dependent transcription, which blocks BIO-induced β-catenin stabilization; reduces nuclear and cytosolic β-catenin levels in mouse L-cells, and inhibits growth and reduces TCF-dependent transcription in SW480 colon carcinoma cells. Learn More

    Starting at: $105.00

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  • Cardionogen 1

    Cardionogen 1, a wnt signaling modulator, potently inhibits Wnt/β-catenin-dependent transcription in murine ES cells and zebrafish embryos and Enlarges heart size via cardiomyocyte hyperplasia; induces ES cell cardiac differentiation. Learn More

    Starting at: $139.00

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  • iCRT 14

    iCRT 14 is a potent inhibitor of β-catenin-responsive transcription (CRT) with IC50 of 40.3 nM in assays of Wnt pathway activity. Learn More

    Starting at: $139.00

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  • ICG 001

    ICG 001 is an inhibitor of TCF/β-catenin-mediated transcription that inhibits β-catenin/CBP interaction. Learn More

    Starting at: $99.00

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  • JW 67

    JW 67 is an inhibitor of canonical Wnt pathway signaling (IC50 = 1.17 μM); targets the β-catenin destruction complex (GSK-3β/AXIN/APC) to induce β-catenin degradation. Learn More

    Starting at: $109.00

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7 Item(s)

per page