Voltage-gated Calcium Channels (CaV)

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  • Efonidipine hydrochloride monoethanolate

    Efonidipine hydrochloride monoethanolate is a selective blocker of L-type and T-type Ca2+ channels which displays minimal inhibition of N- and P/Q-type channels and no inhibition of R-type channels. Learn More

    Starting at: $85.00

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  • (R)-(+)-Bay K 8644

    (R)-(+)-Bay K 8644 is a L-type Ca2+-channel blocker with negative inotropic and vasodilatatory effects in vivo. Learn More

    Starting at: $189.00

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  • (S)-(-)-Bay K 8644

    (S)-(-)-Bay K 8644 is a L-type Ca2+-channel activator with positive inotropic, vasoconstrictive and behavioral effects in vivo. Learn More

    Starting at: $199.00

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  • Benidipine hydrochloride

    Benidipine hydrochloride is an orally active antihypertensive agent that inhibits L-, N- and T-type Ca2+ channels and also inhibits aldosterone-induced mineralocorticoid receptor activation. Learn More

    Starting at: $109.00

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  • Bepridil hydrochloride

    Bepridil hydrochloride is a calcium channel blocker that inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channels. Learn More

    Starting at: $75.00

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  • (±)-Bay K 8644

    (±)-Bay K 8644 is a L-type Ca2+-channel activator with EC50 value of 17.3 nM. Learn More

    Starting at: $125.00

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  • NNC 55-0396 dihydrochloride

    NNC 55-0396 dihydrochloride is a highly selective T-type calcium channel blocker, which displays IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells. Learn More

    Starting at: $199.00

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  • PD 173212

    PD 173212 is a potent N-type voltage-gated calcium channel blocker (IC50 = 36 nM), which displays selectivity over K+, Na+ and L-type Ca2+ channels and prevents tonic seizures in the audiogenic seizure model in vivo. Learn More

    Starting at: $190.00

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  • ML 218 hydrochloride

    ML 218 hydrochloride is a selective inhibitor of T-type calcium channels (IC50 values are 270 and 310 nM for Cav3.3 and Cav3.2 respectively in a patch EP assay). Learn More

    Starting at: $169.00

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  • Lercanidipine hydrochloride

    Lercanidipine hydrochloride is a L-type Ca2+ channel blocker that displays higher vascular selectivity than felodipine Learn More

    Starting at: $75.00

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  • SR 33805 oxalate

    SR 33805 oxalate is a potent Ca2+ channel antagonist which binds allosterically to the a1-subunit of L-type Ca2+ channels (Kd = 20 pM), at a site distinct from other types of blocker. It also inhibits PDGF-stimulated smooth muscle cell proliferation. Learn More

    Starting at: $150.00

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  • FPL 64176

    FPL 64176 is a potent activator of L-type Ca2+ channels (EC50 = 16 nM). Learn More

    Starting at: $85.00

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  • Amlodipine besylate

    Amlodipine besylate is a L-type calcium channel blocker that displays antihypertensive properties, which inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Learn More

    Starting at: $50.00

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  • Ruthenium Red

    Ruthenium Red Blocks Ca2+ uptake and release from mitochondria, and Ca2+ release from ryanodine-sensitive intracellular stores. Also blocks cell membrane-located capsaicin-activated cation channels (IC50 = 14 nM) and voltage-sensitive Ca2+ channels to inhibit neurotransmitter release. Learn More

    Starting at: $65.00

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  • L-651,582

    L-651,582 is an orally active Ca2+ channel blocker which inhibits K+- and carbachol-stimulated Ca2+ influx (IC50 values are 500 and 935 nM respectively). Learn More

    Starting at: $149.00

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15 Item(s)

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