Voltage-gated Calcium Channels (CaV)
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Efonidipine hydrochloride monoethanolate
Efonidipine hydrochloride monoethanolate is a selective blocker of L-type and T-type Ca2+ channels which displays minimal inhibition of N- and P/Q-type channels and no inhibition of R-type channels. Learn MoreStarting at: $85.00
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(R)-(+)-Bay K 8644
(R)-(+)-Bay K 8644 is a L-type Ca2+-channel blocker with negative inotropic and vasodilatatory effects in vivo. Learn MoreStarting at: $189.00
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(S)-(-)-Bay K 8644
(S)-(-)-Bay K 8644 is a L-type Ca2+-channel activator with positive inotropic, vasoconstrictive and behavioral effects in vivo. Learn MoreStarting at: $199.00
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Benidipine hydrochloride
Benidipine hydrochloride is an orally active antihypertensive agent that inhibits L-, N- and T-type Ca2+ channels and also inhibits aldosterone-induced mineralocorticoid receptor activation. Learn MoreStarting at: $109.00
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Bepridil hydrochloride
Bepridil hydrochloride is a calcium channel blocker that inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channels. Learn MoreStarting at: $75.00
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(±)-Bay K 8644
(±)-Bay K 8644 is a L-type Ca2+-channel activator with EC50 value of 17.3 nM. Learn MoreStarting at: $125.00
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NNC 55-0396 dihydrochloride
NNC 55-0396 dihydrochloride is a highly selective T-type calcium channel blocker, which displays IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells. Learn MoreStarting at: $199.00
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PD 173212
PD 173212 is a potent N-type voltage-gated calcium channel blocker (IC50 = 36 nM), which displays selectivity over K+, Na+ and L-type Ca2+ channels and prevents tonic seizures in the audiogenic seizure model in vivo. Learn MoreStarting at: $190.00
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ML 218 hydrochloride
ML 218 hydrochloride is a selective inhibitor of T-type calcium channels (IC50 values are 270 and 310 nM for Cav3.3 and Cav3.2 respectively in a patch EP assay). Learn MoreStarting at: $169.00
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Lercanidipine hydrochloride
Lercanidipine hydrochloride is a L-type Ca2+ channel blocker that displays higher vascular selectivity than felodipine Learn MoreStarting at: $75.00
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SR 33805 oxalate
SR 33805 oxalate is a potent Ca2+ channel antagonist which binds allosterically to the a1-subunit of L-type Ca2+ channels (Kd = 20 pM), at a site distinct from other types of blocker. It also inhibits PDGF-stimulated smooth muscle cell proliferation. Learn MoreStarting at: $150.00
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FPL 64176
FPL 64176 is a potent activator of L-type Ca2+ channels (EC50 = 16 nM). Learn MoreStarting at: $85.00
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Amlodipine besylate
Amlodipine besylate is a L-type calcium channel blocker that displays antihypertensive properties, which inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Learn MoreStarting at: $50.00
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Ruthenium Red
Ruthenium Red Blocks Ca2+ uptake and release from mitochondria, and Ca2+ release from ryanodine-sensitive intracellular stores. Also blocks cell membrane-located capsaicin-activated cation channels (IC50 = 14 nM) and voltage-sensitive Ca2+ channels to inhibit neurotransmitter release. Learn MoreStarting at: $65.00
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L-651,582
L-651,582 is an orally active Ca2+ channel blocker which inhibits K+- and carbachol-stimulated Ca2+ influx (IC50 values are 500 and 935 nM respectively). Learn MoreStarting at: $149.00