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Valinomycin
Valinomycin is a selective K+ ionophore (K0.5 values are 48, 73, 75, 93 and 246 mM for K+, Rb+, Cs+, Na+ and Li+ respectively) that transports K+ across biological and artificial lipid membranes, which inhibits Ca2+-ATPase activity and induces apoptosis through mitochondrial membrane depolarization, caspase-3 activation and phosphatidylserine translocation in vitro.
Additional Info
Additional Info
| Catalog No. | ES2207 |
|---|---|
| CAS Number | 2001-95-8 |
| Formula | C54H90N6O18 |
| M. Wt | 1111.32 |
| Purity | >98 % |
| Solubility | Soluble to 25 mM in DMSO and to 25 mM in ethanol |
| Chemical Name | Cyclo(D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl) |
| Synonyms | N/A |
| Storage | Desiccate at -20°C |
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