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ER 27319 maleate
ER 27319 maleate is a selective inhibitor of Syk kinase which inhibits tyrosine phosphorylation of Syk initiated by the engagement of FcεRI in rat and human mast cells. Results in the abrogation of degranulation, TNF-α production (IC50 = 10 μM) and other related signaling events.
Additional Info
Additional Info
| Catalog No. | ES2213 |
|---|---|
| CAS Number | 201010-95-9 |
| Formula | C18H20N2O.C4H4O4 |
| M. Wt | 396.17 |
| Purity | >98 % |
| Solubility | Soluble to 75 mM in water and to 100 mM in DMSO |
| Chemical Name | 10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinone maleate |
| Synonyms | N/A |
| Storage | Desiccate at +4°C |
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