SR 140333

SR 140333 is a potent NK1 receptor antagonist (Ki = 0.74 nM. IC50 = 1.6 nM) which inhibits substance P-invoked calcium mobilization and outward current (IC50 = 1.3 nM) and blocks NK1-mediated nitric oxide-dependent vasodilation in vivo.

Availability: In stock

Product Name Price Qty
SR 140333 10mg
$180.00
SR 140333 50mg
$715.00

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Additional Info
Additional Info
Catalog No. ES1850
CAS Number 153050-21-6
Formula C37H45Cl3N2O2
M. Wt 656.12
Purity >98 %
Solubility Soluble to 100 mM in DMSO and to 100 mM in ethanol
Chemical Name 1-[2-[(3S)-3-(3,4-Dichlorophenyl)-1​-[2-[3-(1-methylethoxy)phenyl]acetyl]-3-piperidiny​l]ethyl]-4-phenyl-1-azoniabicyclo[2.2.2]octane chloride
Synonyms N/A
Storage Store at -20°C
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