Prostanoid Receptors
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L-655,240
L-655,240 is a potent and selective thromboxane A2/prostaglandin endoperoxide receptor antagonist. pA2 values are 8 - 8.4 in guinea pig smooth muscle; IC50 = 7 nM for inhibition of human platelet aggregation. Orally active in vivo. Learn MoreStarting at: $105.00
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Prostaglandin F2α
Prostaglandin E2 and F2α receptor agonist. Naturally-occurring prostaglandin and potent vasoconstrictor. Learn MoreStarting at: $159.00
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16,16-Dimethyl Prostaglandin E2
16,16-Dimethyl Prostaglandin E2 is a synthetic derivative of prostaglandin E2, which increases embryonic stem cell (ESC) hematopoietic colony formation in mouse bone marrow. Learn MoreStarting at: $85.00
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GW 627368
GW 627368 is a selective prostanoid EP4 receptor competitive antagonist with additional affinity at TP receptors (pKi values are 7.0 and 6.8 in competition radioligand bioassays). Learn MoreStarting at: $179.00
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(+)-Fluprostenol
(+)-Fluprostenol, a prostaglandin F2α (FP) receptor agonist, stimulates intracellular calcium mobilization in cloned human ocular FP receptors, rat A7r5 cells and mouse 3T3 cells (EC50 values are 17.5, 19.1 and 37.3 nM respectively). Learn MoreStarting at: $55.00
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U 46619
U 46619 is a stable synthetic analog of the endoperoxide prostaglandin PGH2 first prepared in 1975, and acts as a thromboxane A2 (TP) receptor agonist. Learn MoreStarting at: $109.00
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Misoprostol
Misoprostol is a cytoprotective prostaglandin E1 analog with Ki values of 120, 250, 67 and 67 nM at cloned mouse EP1, EP2, EP3 and EP4 receptors respectively. Learn MoreStarting at: $99.00
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Sulprostone
Sulprostone is a selective EP3 and EP1 receptor agonist and also is synthetic PGE2 analog and allodynic agent. Learn MoreStarting at: $119.00
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Epoprostenol
Epoprostenol is a endogenous prostanoid that is a potent agonist at IP prostanoid receptors. Learn MoreStarting at: $389.00
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Ozagrel hydrochloride
Ozagrel hydrochloride is a potent and selective inhibitor of thromboxane (TXA2) synthetase that inhibits platelet aggregation in vitro and arachidonate-induced arterial contraction in vivo. Learn MoreStarting at: $85.00
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TCS 2510
TCS 2510 is a highly selective EP4 agonist (EC50 = 2.5 nM; Ki = 1.2 nM), which displays no significant binding at other prostaglandin receptors at concentrations up to 14 μM. Learn MoreStarting at: $139.00
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L-798,106
L-798,106 is a potent and highly selective prostanoid EP3 receptor antagonist (Ki values are 0.3, 916, > 5000 and > 5000 nM at EP3, EP4, EP1 and EP2 respectively). Learn MoreStarting at: $140.00
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SC 19220
SC 19220 is a selective EP1 receptor antagonist (IC50 = 6.7 μM for inhibition of [3H]-PGE2 binding to EP1 transfected COS cells). Learn MoreStarting at: $129.00
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ICI 185,282
ICI 185,282 is a potent thromboxane receptor antagonist. Learn MoreStarting at: $95.00
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AA 2414
AA 2414 is a thromboxane A2 (TP) receptor antagonist, which inhibits platelet aggregation and bronchoconstriction induced by a TXA2 mimetic in guinea pigs. Learn MoreStarting at: $90.00
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ICI 192,605
ICI 192,605 is a potent thromboxane A2 receptor (TP receptor) antagonist. Competitively inhibits contractile responses to U 46619. Learn MoreStarting at: $95.00
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L-670,596
L-670,596 is a potent and selective thromboxane A2/prostaglandin endoperoxide receptor antagonist (IC50 = 5.5 nM), which inhibits U-44069-induced contractions of guinea pig trachea (pA2 = 9.0) and human platelet aggregation in vitro (IC50 = 6.5 nM). Learn MoreStarting at: $135.00
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Latanoprost
Latanoprost is a FP prostaglandin receptor agonist, which exhibits agonist activity at EP1 and EP3 receptors and displays greater selectivity than prostanglandin F2α . Learn MoreStarting at: $175.00
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SC 51322
SC 51322 is a potent EP1 prostanoid receptor antagonist (Ki = 13.8 nM), which displays analgesic properties in vivo. Learn MoreStarting at: $105.00
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SC 51089
SC 51089 is a selective EP1 prostanoid receptor antagonist (Ki values are 1.3, 11.2, 17.5, 61.1, > 100, > 100, > 100, >100 and > 100 μM for EP1, TP, EP3, EP2, EP4, FP and DP receptors respectively). Learn MoreStarting at: $115.00