Potassium Channels

PNU 37883 hydrochloride

PNU 37883 hydrochloride acts as a novel antagonist selective for the vascular form of Kir6 (KATP) channel. It inhibits Kir6 currents in isolated mesenteric artery smooth muscle cells (Kd = 65 nM) but not in cardiac or skeletal myocytes. Learn More

Starting at: $125.00

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Cesium chloride

Cesium chloride is a potassium channel blocker that prevents activation of caspase-3 and neuronal apoptosis in serum- and potassium-deprived cerebellar granule neurons by inactivating GSK-3β. Learn More

Starting at: $39.00

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BL 1249

BL 1249 is a putative potassium channel activator which exhibits selectivity for bladder over vascular tissue in vitro and in vivo (EC50 values are 1.26 and 21.0 μM for cultured bladder and aortic tissues respectively). Learn More

Starting at: $115.00

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YS-035 hydrochloride

YS-035 hydrochloride is a Ca2+ blocker that strikingly prolongs cardiac action potentials by inhibiting pacemaker current and K+ outward currents. Learn More

Starting at: $79.00

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DMP 543

Indirubin-3'-oxime is aprotein kinase inhibitor and inhibits cyclin-dependent kinases (IC50 = 0.18 - 3.33 μM) and GSK-3β (IC50 = 0.19 μM). Learn More

Starting at: $95.00

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