Poly(ADP-ribose) Polymerase

BYK 204165

BYK 204165 is a potent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 values are 5.38 and 7.35 for PARP-2 and PARP-1 respectively). Learn More

Starting at: $95.00

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EB 47

EB 47 is a potent inhibitor of PARP-1 (IC50 = 45 nM), which reduces infarct volume in both a rat transient middle cerebral arterial occlusion model and a cardiac reperfusion model. Learn More

Starting at: $145.00

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DR 2313

DR 2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 values are 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). Learn More

Starting at: $49.00

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4-HQN

4-HQN is an inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 = 9.5 μM), which displays mixed inhibition with respect to NAD+. Protective against ischemia-reperfusion induced ROS production, and subsequent mitochondrial and cell damage in rat heart. Learn More

Starting at: $69.00

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BYK 49187

Chromanol 293B is a blocker of the slow delayed rectifier K+ current (IKs) (IC50 = 1-10 μM), which blocks the CFTR chloride current (ICFTR) (IC50 = 19 μM). Learn More

Starting at: $70.00

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TC-E 5001

TC-E 5001 is a dual tankyrase (TNKS) inhibitor that inhibits wnt signaling and stabilizes Axin2 levels. Learn More

Starting at: $99.00

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NU 1025

NU 1025 is a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP). Learn More

Starting at: $105.00

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