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YM 58483
YM 58483 is a blocker of store-operated Ca2+ entry (SOCE), which mediates the activation of non-excitable cells (e.g. lymphocytes) and inhibits calcium release-activated calcium (CRAC) channels; suppresses thapsigargin-induced sustained Ca2+ influx (IC50 = 100 nM).
Additional Info
Additional Info
| Catalog No. | ES2331 |
|---|---|
| CAS Number | 223499-30-7 |
| Formula | C15H9F6N5OS |
| M. Wt | 421.32 |
| Purity | >98 % |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Chemical Name | N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide |
| Synonyms | Btp2 |
| Storage | Store at +4°C |
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