Nuclear Receptors

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  • SR 8278

    SR 8278 is a Rev-Erbα antagonist; inhibits Rev-Erbα transcriptional repression (EC50 = 0.47 μM) and blocks activity of Rev-Erbα agonist GSK 4112 in HEK293 cells. Learn More

    Starting at: $115.00

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  • GSK 4112

    GSK 4112 is a selective Rev-Erbα agonist (EC50 = 250 nM) which enhances recruitment of nuclear receptor co-repressor (NCoR) peptide to Rev-Erbα; causes acute suppression of Bmal1 gene transcription. Learn More

    Starting at: $100.00

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  • 22-Oxacalcitriol

    22-Oxacalcitriol is non-calcemic vitamin D3 analog and VDR ligand, which inhibits tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid. Learn More

    Starting at: $125.00

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  • Calcipotriol

    Calcipotriol is a Vitamin D3 analog that displays minimal effects on calcium homeostasis, which regulates cell differentiation and proliferation; exhibits antiproliferative activity against human HL-60, HL60/MX2, MCF-7, T47D, SCC-25 and mouse WEHI-3 cancer cell lines. Learn More

    Starting at: $115.00

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  • Tacalcitol

    Tacalcitol promotes normal bone development by regulating calcium and modulates immunological and inflammatory processes. Learn More

    Starting at: $169.00

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