You have no items in your shopping cart.
NK1 Receptors
-
CP 96345
CP 96345 is a potent and selective non-peptide NK1 receptor antagonist. Learn MoreStarting at: $135.00
-
RP 67580
RP 67580 is a potent and selective tachykinin NK1 receptor antagonist (Ki values are 2.9 nM and > 10 μM for rat NK1, and rat NK2 and NK3 receptors respectively), which displays higher affinity at rat and mouse than human receptors. Learn MoreStarting at: $135.00
-
CP 99994 dihydrochloride
CP 99994 dihydrochloride is a high affinity NK1 antagonist (Ki = 0.145 nM in vitro) which displays high ex vivo binding potency in gerbil striatum (IC50 = 36.8 nM). Learn MoreStarting at: $150.00
-
FK 888
FK 888 is a selective, high affinity tachykinin NK1 receptor antagonist (Ki = 0.69 nM) that displays 320-fold selectivity for human over rat NK1 receptors which inhibits substance P-induced contraction of isolated guinea pig trachea (IC50 = 32 nM) and inhibits substance P-induced airway constriction in vivo following i.v. and oral administration. Learn MoreStarting at: $195.00
-
L-732,138
L-732,138 is a potent and highly selective competitive tachykinin NK1 receptor antagonist (IC50 = 2.3 nM). Learn MoreStarting at: $65.00
-
L-733,060 hydrochloride
L-733,060 hydrochloride is a potent antagonist of human tachykinin NK1 receptors (Ki values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors respectively) which produces anxiolytic-like effects in the gerbil elevated plus-maze. Learn MoreStarting at: $140.00
-
SR 140333
SR 140333 is a potent NK1 receptor antagonist (Ki = 0.74 nM. IC50 = 1.6 nM) which inhibits substance P-invoked calcium mobilization and outward current (IC50 = 1.3 nM) and blocks NK1-mediated nitric oxide-dependent vasodilation in vivo. Learn MoreStarting at: $180.00
-
SDZ NKT 343
SDZ NKT 343 is a highly selective human tachykinin NK1 receptor antagonist (IC50 values are 0.62 and 451 nM for human and rat receptors respectively) that displays > 130-fold selectivity over human NK2 and NK3 receptors. Learn MoreStarting at: $195.00
-
L 760735
L 760735 is a high affinity NK1 receptor antagonist (IC50 = 0.19 nM at human NK1 receptors), which is selective (>300-fold) over h-NK2 and h-NK3 receptors and exhibits anxiolytic and antidepressant-like effects. Learn MoreStarting at: $145.00
