Mulberroside A
Mulberroside A is a stilbenoid found in Morus alba, the white mulberry.[1] It is the diglucoside of oxyresveratrol.
Mulberroside A, a glycosylated stilbene, was isolated and identified from the ethanol extract of the roots of Morus alba. Oxyresveratrol, the aglycone of mulberroside A, was produced by enzymatic hydrolysis of mulberroside A using the commercial enzyme Pectinex®. Mulberroside A and oxyresveratrol showed inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 and 0.49 μM, respectively. The tyrosinase inhibitory activity of oxyresveratrol was thus approximately 110-fold higher than that of mulberroside A. Inhibition kinetics showed mulberroside A to be a competitive inhibitor of mushroom tyrosinase with l-tyrosine and l-DOPA as substrate. Oxyresveratrol showed mixed inhibition and noncompetitive inhibition against l-tyrosine and l-DOPA, respectively, as substrate. The results indicate that the tyrosinase inhibitory activity of mulberroside A was greatly enhanced by the bioconversion process.
Reference
- Kim, JK; Kim, M; Cho, SG; Kim, MK; Kim, SW; Lim, YH (2010). "Biotransformation of mulberroside a from Morus alba results in enhancement of tyrosinase inhibition". Journal of industrial microbiology & biotechnology 37 (6): 631–7.doi:10.1007/s10295-010-0722-9. PMID 20411402.
Catalog No. | EN10091 |
---|---|
Source | Morus alba L. |
CAS Number | 102841-42-9 |
Formula | C26H32O14 |
M. Wt | 568.528 |
Purity | >98% |
Appearance | White powder |
Storage | Store at -20°C |
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