MBT Domains

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  • UNC 926 hydrochloride

    UNC 926 hydrochloride is a methyl-lysine (Kme) reader domain inhibitor; binds to the MBT domain of the L3MBTL1 protein (Kd = 3.9 μM), which selectively inhibits the L3MBTL13XMBT-H4K20me1 interaction in a peptide pull down assay. Learn More

    Starting at: $110.00

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  • SGC 0946

    SGC 0946 is a potent DOT1L methyltransferase inhibitor (KD = 0.06 nM, IC50 = 0.3 nM in a radioactive assay) which blocks H3K79 methylation in A431 cells and MCF10A cells (IC50 values are 2.65 and 8.8 nM respectively). Learn More

    Starting at: $199.00

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2 Item(s)

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