M1 Receptors
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Cevimeline hydrochloride
Cevimeline hydrochloride is a selective M1 receptor agonist which induces atropine-sensitive contractions of isolated guinea pig ilea and trachea preparations (EC50 values are 3.5 and 3 μM respectively). Learn MoreStarting at: $95.00
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VU 0357017 hydrochloride
VU 0357017 hydrochloride is a positive allosteric modulator of muscarinic M1 receptors (EC50 = 198 nM), which displays no activity at M2-M5 at concentrations up to 30 μM. Learn MoreStarting at: $110.00
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VU 0255035
VU 0255035 is a highly selective muscarinic M1 antagonist (Ki = 14.87 nM), which targets the M1 orthosteric site and reduces pilocarpine-induced seizures in mice. Learn MoreStarting at: $110.00
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Telenzepine dihydrochloride
Telenzepine dihydrochloride is a selective high affinity muscarinic M1 receptor antagonist (Ki = 0.94 nM) which inhibits gastric acid secretion. Learn MoreStarting at: $50.00
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Pirenzepine dihydrochloride
Pirenzepine dihydrochloride is a M1 muscarinic receptor selective antagonist. Learn MoreStarting at: $65.00
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McN-A 343
McN-A 343 is a selective muscarinic M1 receptor agonist with selectivity for M1 over other muscarinic receptor types appears to arise from a high efficacy at M1 receptors. Learn MoreStarting at: $37.00
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Nitrocaramiphen hydrochloride
Nitrocaramiphen hydrochloride is a muscarinic antagonist with 71-fold selectivity for M1 over M2. Learn MoreStarting at: $95.00