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17-DMAG hydrochloride
17-DMAG hydrochloride is a water-soluble analog of 17-AAG and geldanamycin, which binds the ATP binding site of Hsp90 and inhibits its chaperone activity, and displays more potent antitumor activity than 17-AAG (mean GI50 values are 53 and 123 nM for 17-DMAG and 17-AAG respectively).
Additional Info
Additional Info
| Catalog No. | ES2901 |
|---|---|
| CAS Number | 467214-20-6 |
| Formula | C32H48N4O8.HCl |
| M. Wt | 653.21 |
| Purity | >98 % |
| Solubility | Soluble to 30 mM in DMSO and to 10 mM in ethanol |
| Chemical Name | 17-Demethoxy-17-[[2-(dimethylamino)ethyl]amino]geldanamycin hydrochloride |
| Synonyms | NSC 707545 |
| Storage | Desiccate at -20°C |
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