Histamine H3 Receptors
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Thioperamide
Thioperamide is a potent histamine H3 and H4 antagonist/inverse agonist, which blocks eosinophil shape change (IC50 = 1.4 μM) and chemotaxis (IC50 = 519 nM) induced by histamine. Learn MoreStarting at: $90.00
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(S)-(+)-α-Methylhistamine dihydrobromide
(S)-(+)-α-Methylhistamine dihydrobromide is a less active enantiomer of H3 agonist R-(-)-α-methylhistamine. Learn MoreStarting at: $89.00
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(R)-(-)-α-Methylhistamine dihydrobromide
(R)-(-)-α-Methylhistamine dihydrobromide is a very potent, high affinity H3 agonist that inhibits H3-mediated histamine synthesis and release in the CNS and stimulates H4-mediated eosinophil shape change. Learn MoreStarting at: $89.00
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Nα-Methylhistamine dihydrochloride
Nα-Methylhistamine dihydrochloride is a potent histamine agonist, particularly at H3 receptors that displays agonist properties at H4 receptors to which it binds with moderate affinity with Ki value of 23 nM. Learn MoreStarting at: $89.00
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VUF 5681 dihydrobromide
VUF 5681 dihydrobromide is a potent histamine H3 receptor silent antagonist. Learn MoreStarting at: $129.00
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Carcinine ditrifluoroacetate
Carcinine ditrifluoroacetate is a highly selective H3 receptor antagonist with Ki values of 0.30, 365 and 3621 μM for H3, H2 and H1 receptors respectively. Learn MoreStarting at: $129.00
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Conessine
Conessine is a potent and selective histamine H3 receptor antagonist. It is a steroidal alkaloid that displays in vitro antiplasmodial activity (IC50 = 1.04 μM). Learn MoreStarting at: $92.00
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JNJ 10181457 dihydrochloride
JNJ 10181457 dihydrochloride is a brain penetrant Histamine H3 receptor antagonist with pKi values of 8.15 and 8.93 for rat and human H3 receptors respectively. Learn MoreStarting at: $110.00
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Immepip dihydrobromide
Phorbol 12-myristate 13-acetate is an extensively used phorbol ester activator of protein kinase C; tumor promoter. Learn MoreStarting at: $105.00
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JNJ 5207852 dihydrochloride
JNJ 5207852 dihydrochloride is a high affinity histamine H3 receptor neutral antagonist (pKi values are 8.9 and 9.2 in rat and human respectively). Learn MoreStarting at: $120.00
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Impentamine dihydrobromide
Impentamine dihydrobromide is a potent and highly selective histamine H3 receptor antagonist (pA2 = 8.4); displays > 30000-fold selectivity over H1 and H2 receptors. Learn MoreStarting at: $99.00
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Imetit dihydrobromide
Imetit dihydrobromide is an extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively), which induces shape change in eosinophils with an EC50 of 25 nM. Learn MoreStarting at: $90.00
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ROS 234 dioxalate
ROS 234 dioxalate is a potent H3 antagonist (pKB at guinea-pig ileum H3-receptor = 9.46). Learn MoreStarting at: $95.00
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Proxyfan oxalate
Proxyfan oxalate is a high affinity histamine H3 receptor ligand (pKi = 8.62) that acts as a protean agonist at recombinant and native receptors. Learn MoreStarting at: $95.00
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GT 2016
GT 2016 is a high affinity H3 receptor antagonist (Ki = 43.8 nM) which displays selectivity against H1 and H2 receptors (IC50 >10 μM). Increases the release of histamine in the cerebral cortex. Learn MoreStarting at: $115.00
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Methimepip dihydrobromide
Methimepip dihydrobromide is an extremely selective histamine H3 receptor agonist (pKi values are 9.0, 5.7, < 5.0 and < 5.0 for hH3, hH4, hH1 and hH2 receptors respectively). Learn MoreStarting at: $120.00
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Clobenpropit dihydrobromide
Clobenpropit dihydrobromide is an extremely potent histamine H3 antagonist/inverse agonist (pA2=9.93), which displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM. Learn MoreStarting at: $115.00
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Iodophenpropit dihydrobromide
Iodophenpropit dihydrobromide is a selective H3 antagonist with high affinity (KD = 0.3 nM). Learn MoreStarting at: $110.00
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BF 2649 hydrochloride
BF 2649 hydrochloride is a histamine H3 receptor inverse agonist and antagonist that exhibits nootropic effects in cognitive disorders; reduces locomotor hyperactivity induced by methamphetamine. Learn MoreStarting at: $105.00