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VU 0285683
VU 0285683 is a negative allosteric modulator of mGlu5 receptors, which displays high affinity for the MPEP binding site and acts as a full antagonist and blocks the glutamate response to mGlu5 (IC50 = 24.4 nM).
Additional Info
Additional Info
| Catalog No. | ES2624 |
|---|---|
| CAS Number | 327056-22-4 |
| Formula | C14H7FN4O |
| M. Wt | 266.23 |
| Purity | >98 % |
| Solubility | Soluble to 50 mM in DMSO and to 25 mM in ethanol |
| Chemical Name | 3-Fluoro-5-[3-(2-pyridinyl)-1,2,4-oxadiazol-5-yl]-benzonitrile |
| Synonyms | N/A |
| Storage | Store at RT |
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