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LY 456236 hydrochloride
LY 456236 hydrochloride is a selective mGlu1 receptor antagonist (IC50 values are 143 nM and > 10 μM for mGlu1 and mGlu5 receptors respectively), which reduces hyperalgesic behavior induced by formalin in both mouse and rat with ED50 values of 28 and 16.3 mg/kg respectively.
Additional Info
Additional Info
| Catalog No. | ES2664 |
|---|---|
| CAS Number | 338738-57-1 |
| Formula | C16H15N3O2.HCl |
| M. Wt | 317.77 |
| Purity | >98 % |
| Solubility | Soluble to 20 mM in DMSO |
| Chemical Name | 6-Methoxy-N-(4-methoxyphenyl)-4-quinazolinamine hydrochloride |
| Synonyms | MPMQ hydrochloride |
| Storage | Desiccate at RT |
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