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JNJ 16259685
JNJ 16259685 is a sub-nanomolar potent, non-competitive mGlu1 antagonist (Ki = 0.34 nM), which inhibits glutamate-induced Ca2+ response at the human mGlu1 receptor with an IC50 value of 0.55 nM.
Additional Info
Additional Info
| Catalog No. | ES2824 |
|---|---|
| CAS Number | 409345-29-5 |
| Formula | C20H23NO3 |
| M. Wt | 325.41 |
| Purity | >98 % |
| Solubility | Soluble to 100 mM in ethanol and to 25 mM in DMSO |
| Chemical Name | (3,4-Dihydro-2H-pyrano[2,3-b]quinolin-7-yl)-(cis-4-methoxycyclohexyl)-methanone |
| Synonyms | N/A |
| Storage | Store at +4°C |
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