GABA Transporters

CI 966 hydrochloride

CI 966 hydrochloride is a selective inhibitor of the GABA transporter GAT-1 (IC50 values are 0.26 and 1.2 μM at cloned human and rat GAT-1 respectively). Learn More

Starting at: $120.00

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NNC 711

NNC 711 is a potent and selective inhibitor of GABA uptake by GAT-1 (IC50 values are 0.04, 171, 1700 and 622 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Learn More

Starting at: $135.00

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Tiagabine hydrochloride

Tiagabine hydrochloride is a GABA uptake inhibitor (IC50 = 67 nM in vivo), which exhibits high affinity and selectivity for the GAT-1 GABA transporter. Learn More

Starting at: $169.00

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NNC 05-2090 hydrochloride

NNC 05-2090 hydrochloride is a GABA uptake inhibitor that displays moderate selectivity for BGT-1 (mGAT-2) transporters (Ki values are 1.4, 15, 19 and 41 μM for hBGT-1, hGAT-3, hGAT-1 and hGAT-2 respectively). Learn More

Starting at: $140.00

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Guvacine hydrochloride

Guvacine hydrochloride is a specific GABA uptake inhibitor. IC50 values are 14, 58, 119 and 1870 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively. Learn More

Starting at: $125.00

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(S)-SNAP 5114

BTS is a selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC50 ~ 5 mM), reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle. Learn More

Starting at: $135.00

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(±)-Nipecotic acid

(±)-Nipecotic acid is a GABA uptake inhibitor with IC50 values of 8, 38, 106 and 2370 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively. Learn More

Starting at: $56.00

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