Estrogen Receptors

18 Item(s)

per page

  • GSK 4716

    GSK 4716 is a selective agonist at estrogen-related receptors ERRβ and ERR&gamma, which displays selectivity over ERRα and the classical estrogen receptors. Learn More

    Starting at: $63.00

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  • Y 134

    Y 134 is a selective estrogen receptor modulator (SERM) that acts as an agonist in the bone and antagonist in reproductive tissue. Learn More

    Starting at: $139.00

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  • PHTPP

    PHTPP is a selective estrogen ERβ receptor antagonist that exhibits full antagonism at ERβ in a cotransfection assay in human endometrial cancer cells (HEC-1), with minimal effects on ERα. Learn More

    Starting at: $145.00

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  • Estropipate

    Estropipate is an estrogen receptor agonist that inhibits organic anion transporting polypeptide 1B1 (OATP1B1). Learn More

    Starting at: $75.00

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  • (Z)-4-Hydroxytamoxifen

    (Z)-4-Hydroxytamoxifen is an estrogen receptor antagonist. Learn More

    Starting at: $139.00

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  • α-Estradiol

    α-Estradiol is a endogenous estrogen receptor ligand. Learn More

    Starting at: $49.00

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  • ERB 041

    IC50 values of ERB 041 are 5 and 1216 nM for human ERβ and ERα; 3.1 and 620 nM for rat ERβ and ERα; and 3.7 and 750 nM for mouse ERβ and ERα respectively. Learn More

    Starting at: $139.00

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  • (R)-DPN

    (R)-DPN, a enantiomer of DPN, displays higher affinity for estrogen receptor (ER) β over ERα with Ki values of 1.82 and 147 nM respectively . Learn More

    Starting at: $186.00

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  • WAY 200070

    WAY 200070 is a selective ERβ receptor agonist that displays 68-fold selectivity over ERα (EC50 values are 2 and 155 nM for ERβ and ERα respectively). Learn More

    Starting at: $109.00

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  • MPP dihydrochloride

    MPP dihydrochloride is a selective, high affinity silent antagonist at ERα receptors. Displays > 200-fold selectivity for ERα over ERβ. Ki values are 2.7 and 1800 nM at ERα and ERβ receptors respectively. Learn More

    Starting at: $109.00

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  • PPT

    PPT is a potent, subtype-selective estrogen receptor agonist (EC50 ~ 200 pM) which displays 410-fold selectivity for ERα over ER&beta, and prevents ovariectomy-induced weight gain and loss of bone mineral density, and induces gene expression in the hypothalamus following systemic administration in vivo. Learn More

    Starting at: $119.00

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  • Cyclofenil

    Cyclofenil is a non-steroidal selective estrogen receptor modulator (SERM) which displays higher affinity for estrogen receptor β (ERβ) than for ERα. Learn More

    Starting at: $65.00

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  • ZK 164015

    ZK 164015 is a potent estrogen receptor silent antagonist which inhibits 17β-estradiol stimulation of luciferase activity (IC50 = 0.025 μM); potently inhibits the growth of estrogen-sensitive human MCF-7 breast cancer cells in vitro (IC50 ~ 1 nM). Learn More

    Starting at: $115.00

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  • RU 58668

    RU 58668 is a pure antiestrogen that downregulates estrogen receptor expression (IC50 = 0.04 nM), which displays potent antiproliferative activity in vitro (IC50 = 0.035 - 0.09 nM in MCF-7 cells) and causes long term regression of tamoxifen-resistant MCF-7 xenografts in vivo. Learn More

    Starting at: $185.00

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  • DPN

    DPN is a highly potent estrogen ERβ receptor agonist with a 70-fold selectivity over ERα (EC50 values are 0.85 and 66 nM respectively), which shown to regulate expression of GluR1, GluR2 and GluR3 in rat hippocampus. Learn More

    Starting at: $90.00

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  • (R,R)-THC

    (R,R)-THC is a non-steroidal, selective estrogen receptor ligand; agonist at ERα receptor (Ki = 9.0 nM) and antagonist at ERβ receptor (Ki = 3.6 nM). Learn More

    Starting at: $225.00

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  • FERb 033

    FERb 033 is a Potent and selective ERβ receptor agonist (Ki = 7.1 nM, EC50 = 4.8 nM), which also displays 62-fold selectivity over ERα. Learn More

    Starting at: $105.00

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  • DY131

    DY131 is a novel selective agonist at estrogen-related receptors ERRβ and ERRγ that displays minimal activity at ERRα, ERα and ERβ at concentrations up to 30 μM. Learn More

    Starting at: $95.00

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18 Item(s)

per page