Esterases
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SGC-CBP30
SGC-CBP30 is a potent CREBBP/EP300 bromodomain inhibitor (IC50 values are 21-69 and 38 nM for CREBBP and EP300 bromodomains respectively), which displays over 40-fold selectivity for CREBBP over BRD4(1). Learn MoreStarting at: $199.00
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VU 0155069
VU 0155069 is a potent and selective phospholipase D1 (PLD1) inhibitor (IC50 values are 46 and 933 nM for PLD1 and PLD2 respectively), which inhibits migration of human and mouse breast cancer cell lines in transwell assays. Learn MoreStarting at: $130.00
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VU 0364739 hydrochloride
VU 0364739 hydrochloride is a potent and selective phospholipase D2 (PLD2) inhibitor (IC50 = 20 nM) which displays 75-fold selectivity against PLD1 (IC50 = 1500 nM). Learn MoreStarting at: $155.00
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PACOCF3
PACOCF3 is a phospholipase A2 inhibitor. Can also alter Ca2+ signaling in renal tubular cells. Learn MoreStarting at: $75.00
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U 73343
U 73343 is an inactive analog of U 73122. Can be used as a negative control. Learn MoreStarting at: $85.00
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YM 26734
YM 26734 is a competitive inhibitor of secretory phospholipase A2 (sPLA2) that exhibits a broad inhibitory profile to several sPLA2s (IC50 values are 0.2, 1, 1, 1 and 3 μM for sPLA2-X, -IIA, -IID, -V and -IIE respectively). Learn MoreStarting at: $135.00
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AACOCF3
AACOCF3 is an inhibitor of cytosolic (85 kDa) phospholipase A2. It also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. Learn MoreStarting at: $65.00
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m-3M3FBS
m-3M3FBS is a activator of phospholipase C (PLC), which stimulates superoxide generation, Ca2+ release and inositol phosphate formation in a variety of cell types, and inhibits growth of the leukemic cell lines U937 and THP-1. Learn MoreStarting at: $98.00
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OBAA
OBAA is a potent inhibitor of phospholipase A2 (IC50 = 70 nM), which reduces bronchospasm in guinea pigs in vivo. Learn MoreStarting at: $90.00
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o-3M3FBS
o-3M3FBS is an inactive analog of m-3M3FBS. Used as a negative control. Learn MoreStarting at: $99.00
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LY 311727
AM 630 is a CB2 antagonist/inverse agonist (Ki = 31.2 nM) that displays 165-fold selectivity over CB1 receptors. Learn MoreStarting at: $140.00
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Edelfosine
Edelfosine is a synthetic lysophospholipid analog that selectively inhibits phosphatidylinositol phospholipase C. Learn MoreStarting at: $89.00
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STF 083010
STF 083010 is an inhibitor of IRE1α endonuclease activity; blocks endogenous XBP1 mRNA splicing. Learn MoreStarting at: $119.00
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Physostigmine hemisulfate
Physostigmine hemisulfate is a cholinesterase inhibitor. Learn MoreStarting at: $33.00
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Galanthamine hydrobromide
Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Learn MoreStarting at: $75.00
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Phenserine
Phenserine is a Physostigmine analog that inhibits acetylcholinesterase.Phenserin also inhibits production of amyloid precursor protein (APP) and A&beta and improves morris water maze performance of scopolamine-treated rats. Learn MoreStarting at: $95.00
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PE 154
PE 154 is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50 values are 280 pM and 16 nM respectively), which targets and labels β-amyloid plaques in histochemical analysis. Learn MoreStarting at: $160.00
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Rivastigmine tartrate
Rivastigmine tartrate is a dual cholinesterase inhibitor (ChEI) which inhibits both butyrylcholinesterase (BChE) and acetylcholinesterase (AChE). Learn MoreStarting at: $70.00
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Acephate
Anticholinesterase insecticide that produces cholinotoxicity, which displays weak inhibition of rat acetylcholinesterase (AChE) but potently inhibits cockroach AChE. Learn MoreStarting at: $59.00
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Tacrine hydrochloride
AIDA is a relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a), having no effect on group II (mGlu2) or group III (mGlu4) receptors expressed individually in baby hamster kidney cells. Learn MoreStarting at: $60.00