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EO 1428
EO 1428 is a selective inhibitor of p38α and p38β2 that displays no activity at p38γ, p38δ, ERK1/2 and JNK1, which iInhibits production of inflammatory cytokines including IL-8, TNF-α, IL-6, IL-1β and IL-10 (IC50 values are 4, 5, 17, 30 and 74 nM respectively).
Additional Info
Additional Info
| Catalog No. | ES2609 |
|---|---|
| CAS Number | 321351-00-2 |
| Formula | C20H16BrClN2O |
| M. Wt | 415.71 |
| Purity | >98 % |
| Solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| Chemical Name | (2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone |
| Synonyms | N/A |
| Storage | Store at +4°C |
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