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EMD 66684
EMD 66684 is a highly potent and very selective non-peptide angiotensin AT1 receptor antagonist (IC50 values are 0.7 and > 10000 nM for AT1 and AT2 receptors respectively), which potently inhibits angiotensin II-induced contractions in isolated rabbit aorta (IC50 = 0.2 nM) and reduces blood pressure in hypertensive rats.
Additional Info
Additional Info
| Catalog No. | ES2120 |
|---|---|
| CAS Number | 187683-79-0 |
| Formula | C28H30N8O2.HCl |
| M. Wt | 547.05 |
| Purity | >98 % |
| Solubility | Soluble to 50 mM in DMSO and to 50 mM in ethanol |
| Chemical Name | 2-Butyl-3,4-dihydro-N,N-dimethyl-4-oxo-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl-4-yl]methyl]-5H-imidazo[4,5-c]pyridine-5-acetamide hydrochloride |
| Synonyms | EMD66684, EMD-66684 |
| Storage | Desiccate at +4°C |
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