Chloride Channels

9 Item(s)

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  • NPPB

    NPPB is an inhibits calcium-sensitive chloride currents (10 μM). Putative GPR35 agonist. Learn More

    Starting at: $105.00

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  • CaCCinh-A01

    Calcium-activated chloride channel (CaCC) inhibitor (IC50 ~ 10 μM), which inhibits CaCC currents in human bronchial and intestinal cells. Learn More

    Starting at: $99.00

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  • Eact

    Eact is a TMEM16A (ANO1) calcium-activated chloride channel (CaCC) activator (EC50 = 3 μM). Ca2+-independent, which displays no effect on CFTR Cl- or ENaC Na+ conductance, and stimulates submucosal gland secretion in human bronchi. Learn More

    Starting at: $125.00

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  • T16Ainh-A01

    T16Ainh-A01 is an inhibitor of Ca2+-dependent Cl- channel (CaCC) transmembrane protein 16A (TMEM16A) (IC50 = 1.8 μM in A253 salivary gland epithelial cells). Learn More

    Starting at: $119.00

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  • DCEBIO

    DCEBIO stimulates Cl- secretion via the activation of hKCa3.1 (IK1) potassium channels and an apical Cl- conductance carried by the CFTR channel. Learn More

    Starting at: $99.00

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  • 9-AC

    9-AC is a Cl- transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac IcI. Learn More

    Starting at: $65.00

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  • KM 11060

    KM 11060 increases the amount of functional CFTR at the plasma membrane (~75%). Learn More

    Starting at: $105.00

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  • DCPIB

    DCPIB is a potent, selective blocker of the volume-sensitive anion channel (VSAC) that reverses cell swelling-induced action potential duration shortening in atrial myocytes and inhibits astroglial swelling in vitro. Learn More

    Starting at: $109.00

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  • PG 01

    PG 01 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. Learn More

    Starting at: $115.00

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9 Item(s)

per page