GGTI 297

GGTI 297 is a geranylgeranyltransferase I (GGTase-I) inhibitor (IC50 values are 135 and 418 nM for GGTase-I and FTase inhibition respectively), which inhibits RhoA prenylation leading to inactivation of RhoA/ROCK and a decrease in basal tone of the internal anal sphincter in vitro.

Availability: In stock

Product Name Price Qty
GGTI 297 1mg
$149.00

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Additional Info
Additional Info
Catalog No. ES3985
CAS Number No
Formula C26H31N3O3S.CF3CO2H
M. Wt 579.63
Purity >95 %
Solubility Soluble to 50 mM in DMSO
Chemical Name N-[4-[2(R)-Amino-3-mercaptopropyl]a​mino-2-(1-naphthalenyl)benzoyl]-L-leucine trifluoroacetate salt
Synonyms N/A
Storage Store at -20°C
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