Search results for 'WIN'

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  • Starting at: $1,040.00

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  • Starting at: $1,213.00

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  • MDL 28170

    MDL 28170 is a potent, selective inhibitor of calpain and cathepsin B that rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo. Learn More

    Starting at: $65.00

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  • DPPI 1c hydrochloride

    DPPI 1c hydrochloride is an inhibitor of dipeptidyl peptidase IV (DPP-IV) that increases plasma GLP-1 levels and improves glucose tolerance in diabetic mice following oral glucose challenge. Learn More

    Starting at: $85.00

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  • PF 514273

    PF 514273 is a potent and selective CB1 receptor antagonist that inhibits food intake in vivo following oral administration. Learn More

    Starting at: $139.00

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  • (R)-(+)-8-Hydroxy-DPAT hydrobromide

    (R)-(+)-8-Hydroxy-DPAT hydrobromide is a full 5-HT1A serotonin receptor agonist that reduces hippocampal 5-HT levels following systemic administration in rats in vivo. It is more active enantiomer of 8-Hydroxy-DPAT hydrobromide. Learn More

    Starting at: $109.00

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  • 8-Hydroxy-DPAT hydrobromide

    8-Hydroxy-DPAT hydrobromide is a standard selective 5-HT1A agonist that reduces hippocampal 5-HT levels following systemic administration in rats in vivo. Learn More

    Starting at: $59.00

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  • WAY 161503 hydrochloride

    WAY 161503 hydrochloride is a potent and selective 5-HT2C receptor agonist with antidepressant effect following systemic administration in vivo. Learn More

    Starting at: $99.00

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  • Remoxipride hydrochloride

    Remoxipride hydrochloride is a dopamine D2 receptor antagonist showing selectivity over D3 and D4 receptors with Ki values of ~ 300, ~ 1600, and ~ 2800 nM for D2, D3 and D4 receptors respectively. Learn More

    Starting at: $105.00

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  • UK 14304

    UK 14304 is a full α2 adrenergic agonist that is centrally active following systemic administration in vivo. Learn More

    Starting at: $89.00

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  • Ticlopidine hydrochloride

    Ticlopidine hydrochloride, a selective P2Y12 receptor antagonist, inhibits ADP-induced platelet aggregation and displays antithrombotic activity following oral administration in vivo. Learn More

    Starting at: $38.00

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  • CV 1808

    CV 1808, a adenosine A2 receptor agonist, is coronary vasodilator, antihypertensive and antipsychotic following systemic administration in vivo. Learn More

    Starting at: $65.00

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  • Pirfenidone

    Pirfenidone is a antifibrotic agent, effective in models of pulmonary and lung fibrosis that regulates cytokine levels following oral administration in vivo. Learn More

    Starting at: $89.00

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  • CD 2665

    SC 236 is a selective COX-2 inhibitor (IC50 values are 0.005 and 17.8 μM for COX-2 and COX-1 respectively) which displays anti-inflammatory properties and potent antimetastatic activity against both experimental metastases and spontaneous metastases arising following primary tumor excision. Learn More

    Starting at: $140.00

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  • MPPG

    MTPG is a group II/group III metabotropic glutamate receptor antagonist, showing selectivity for group II in electrophysiological studies. Learn More

    Starting at: $135.00

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  • MSPG

    MPPG is a potent antagonist of L-AP4-induced effects in rat spinal cord, thalamic and hippocampal neurons, showing selectivity over (1S,3S)-ACPD-induced effects. Potent antagonist of mGlu receptors linked to adenylyl cyclase in adult rat cortical slices. Learn More

    Starting at: $135.00

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  • MAP4

    (S)-SNAP 5114 is a GABA transport inhibitor, showing selectivity for GAT-3 and GAT-2 (IC50 values are 5, 21 and 388 μM for hGAT-3, rGAT-2 and hGAT-1 respectively). Learn More

    Starting at: $135.00

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  • BMS 470539 dihydrochloride

    BMS 470539 dihydrochlorideis a potent, selective melanocortin MC1 receptor agonist (IC50 = 120 nM), which exhibits anti-inflammatory properties following ischemia-reperfusion in the vasculature. Learn More

    Starting at: $169.00

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  • LM 22A4

    LM 22A4 is a potent tropomyosin-related kinase B (TrkB) agonist (IC50 = 47 nM), which induces activation of Trk, Akt and ERK in mouse hippocampus and striatum. Reverses deficits in motor task learning in mice following traumatic brain injury; restores respiratory function in a rat model of Rett syndrome. Learn More

    Starting at: $129.00

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  • Burimamide oxalate

    Burimamide oxalate is a histamine H3/H2 receptor antagonist (Ki values are 0.07, 7.8 and 290 μM for H3, H2 and H1 receptors respectively), which displays partial agonist activity in SK-N-MC cells and produces antinociceptive effects following intraventricular administration (ED50 = 183 nmol/mouse in hot-plate test). Learn More

    Starting at: $115.00

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