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Search results for 'BB gun'
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Starting at: $52.00
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Starting at: $407.00
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Starting at: $800.00
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Starting at: $800.00
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Starting at: $263.00
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I-CBP 112
I-CBP 112 is a CREBBP/EP300 bromodomain inhibitor (IC50 values are 0.142-0.17 and 0.625 μM for CREBBP and EP300 respectively). Learn MoreStarting at: $199.00
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SGC-CBP30
SGC-CBP30 is a potent CREBBP/EP300 bromodomain inhibitor (IC50 values are 21-69 and 38 nM for CREBBP and EP300 bromodomains respectively), which displays over 40-fold selectivity for CREBBP over BRD4(1). Learn MoreStarting at: $199.00
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Bromosporine
Bromosporine is a broad spectrum bromodomain inhibitor, which accelerates FRAP recovery of BRD4 and CREBBP in cells at a concentration of 1 μM. Learn MoreStarting at: $199.00
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Cromakalim
Cromakalim is a prototypical Kir6 (KATP) channel opener that relaxes rabbit isolated portal vein with an IC50 value of 21 nM . Learn MoreStarting at: $139.00
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JNJ 28871063 hydrochloride
JNJ 28871063 hydrochloride is a potent and selective ErbB receptor family inhibitor with IC50 values of 21, 22 and 38 nM for ErbB4, EGFR and ErbB2 respectively. Learn MoreStarting at: $139.00
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HDS 029
HDS 029 is a potent inhibitor of the ErbB receptor family that inhibits EGF-induced erbB1 autophosphorylation in NIH3T3 cells and heregulin-stimulated ErbB autophosphorylation in MDA-MB-453 human breast carcinoma cells. Learn MoreStarting at: $85.00
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HKI 357
HKI 357 is a potent, irreversible inhibitor of ErbB2 (HER2) and EGFR that suppresses ligand-induced EGFR autophosphorylation and cell proliferation in NCI-H1975 cells containing L858R and T790M mutations. Learn MoreStarting at: $189.00
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Damnacanthal
Damnacanthal is a potent inhibitor of p56lck tyrosine kinase activity (IC50 = 17 nM for inhibition of autophosphorylation), which displays 7- to 20-fold selectivity over p59fyn and p60src tyrosine kinases, > 40-fold selectivity over c-ErbB2, EGF- and insulin-receptor tyrosine kinases, and > 100-fold selectivity over PKA and PKC. Learn MoreStarting at: $115.00
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GW 583340 dihydrochloride
GW 583340 dihydrochloride is a potent dual EGFR/ErbB2 tyrosine kinase inhibitor (IC50 values are 0.01 and 0.014 μM respectively), which selectively inhibits growth of human tumor cells overexpressing EGFR and ErbB2 (IC50 values are 0.11 μM for inhibition of HN5, N87 and BT474 tumor cell lines vs. > 30 μM for inhibition of non-tumor cell line HFF). Learn MoreStarting at: $139.00
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SSR 69071
SSR 69071 is a high affinity, potent inhibitor of human leukocyte elastase (HLE) (IC50 = 3.9 nM), which displays species-selectivity (Ki values are 0.017, 1.70, 3.01, 58 and > 100 nM for human, mouse, rat, rabbit and porcine elastase respectively) and inhibits HLE-induced lung hemorrhage in mice (ID50 = 2.8 mg/kg) and reduces infarct size in an in vivo acute model of coronary ischemia-reperfusion injury. Orally active. Learn MoreStarting at: $139.00
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BAY 41-2272
BAY 41-2272 is an activator of soluble guanylyl cyclase (sGC)which acts at a nitric oxide (NO)-independent regulatory site in the sGC α1 subunit and inhibits platelet aggregation (IC50 = 36 nM) and phenylephrine-induced contractions of rabbit aorta (IC50 = 0.30 μM). Learn MoreStarting at: $139.00
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Probucol
Probucol is an antioxidant, anti-inflammatory and hypocholesterolemic agent, which inhibits atherogenesis in genetically hypercholesterolemic rabbits (Watanabe) and attenuates ischemia/reperfusion-induced cardiomyocyte apoptosis. Learn MoreStarting at: $59.00
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PD 176252
PD 176252 is a non-peptide gastrin-releasing peptide receptor (GRP-R, BB2) and neuromedin B receptor (NMB-R, BB1) antagonist (Ki values are 0.17 and 1.0 nM for BB1 and BB2 respectively), which inhibits proliferation of rat C6 glioma cells (IC50 = 2 μM) and inhibits NCI-H1299 xenograft proliferation in nude mice (IC50 = 5 μM). Learn MoreStarting at: $189.00
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EMD 66684
EMD 66684 is a highly potent and very selective non-peptide angiotensin AT1 receptor antagonist (IC50 values are 0.7 and > 10000 nM for AT1 and AT2 receptors respectively), which potently inhibits angiotensin II-induced contractions in isolated rabbit aorta (IC50 = 0.2 nM) and reduces blood pressure in hypertensive rats. Learn MoreStarting at: $135.00
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TBB
TBB is a cell-permeable, selective inhibitor of casein kinase-2 (CK2) (IC50 = 0.9 and 1.6 μM for rat liver and human recombinant CK2 respectively). Learn MoreStarting at: $65.00
