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SCH 39166 hydrobromide
SCH 39166 hydrobromide is a high affinity dopamine D1/D5 receptor antagonist which displays Ki values of 1.2, 2, 980, 5520, 80 and 731 nM for binding to D1, D5, D2, D4, 5-HT and α2a receptors, respectively. Learn MoreStarting at: $149.00
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PF 04885614
PF 04885614 is a potent NaV1.8 inhibitor (IC50 = 53 nM for human NaV1.8 channel), which exhibits selectivity for hNaV1.8 over hNaV1.6, hNaV1.7, hNaV1.1, hNaV1.2 and hNaV1.5 (IC50 values are 4.2, 7.0, 11, 16 and 27 μM respectively). Learn MoreStarting at: $125.00
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XAC
XAC is an adenosine receptor antagonist (IC50 values are 1.8 and 114 nM at A1 and A2 receptors respectively). Learn MoreStarting at: $95.00
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NS 11021
NS 11021 is an activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1). Learn MoreStarting at: $139.00
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PI 828
PI 828 is a PI 3-Kinase inhibitor with IC50 values of 0.098, 0.183, 0.227 and 1.967 μM for p110β, p110α, p110δ and p110γ respectively. Learn MoreStarting at: $69.00
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G-1
G-1 is a potent and selective GPR30 receptor agonist that increases cytosolic Ca2+ and inhibits migration of SKBr3 cells and MCF-7 cells in response to chemoattractants with IC50 values of 0.7 and 1.6 nM respectively in vitro. Learn MoreStarting at: $139.00
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ML 221
ML 221 is an apelin receptor (APJ) antagonist with IC50 values of 0.70 and 1.75 μM in a cAMP assay and β-arrestin assay, respectively). Learn MoreStarting at: $139.00
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ZK 756326
ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist with IC50 values of 1.8 and 2.6 μM for human and mouse receptors respectively. Learn MoreStarting at: $105.00
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AC 261066
AC 261066 is a potent RARβ2 agonist with a pEC50 value of 8.1. Learn MoreStarting at: $139.00
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A 844606
A 844606 is a selective α7 nicotinic acetylcholine receptor (nAChR) agonist with EC50 values of 1.4 and 2.2 μM at human and rat receptors respectively. Learn MoreStarting at: $129.00
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ARP 101
ARP 101 is a selective inhibitor of MMP-2 that displays ~ 600-fold selectivity over MMP-1. Learn MoreStarting at: $115.00
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CI 898 trihydrochloride
CI 898 trihydrochloride is a potent lipophilic inhibitor of dihydrofolate reductase (DHFR) that inhibits protozoal, bacterial and human DHFR with IC50 values of 1.4, 6.1 and 3.2 nM respectively. Learn MoreStarting at: $139.00
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Iloprost
Iloprost is a prostacyclin (PGI2) analog that inhibits platelet aggregation induced by collagen, thrombin and ADP with IC50 values of 0.24, 0.71 and 1.07 nM respectively. Learn MoreStarting at: $239.00
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K 858
K 858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor that induces mitotic arrest, caspase-3 activation and cell growth inhibition in HCT116 cells with a IC50 value of 1.3 μM. Learn MoreStarting at: $99.00
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Psora 4
Psora 4 is a potent KV1.3 channel blocker (EC50 = 3 nM) that preferentially binds the C-type inactivated state of the channel. Learn MoreStarting at: $145.00
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Bucindolol
Bucindolol is a non-selective β-adrenoceptor antagonist with additional α1-adrenoceptor blocking activity. Ki values are 1.61, 1.20 and 68.9 nM for β1-, β2- and α1-adrenoceptors respectively. Learn MoreStarting at: $139.00
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NS 3763
NS 3763 is a selective non-competitive kainate receptor antagonist that displays selectivity for GLUK5 subunit-containing receptors with IC50 values of 1.6 and > 30 μM for homomeric GLUK5 and GLUK6 receptors respectively. Learn MoreStarting at: $99.00
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SCH 202676 hydrobromide
SCH 202676 hydrobromide is a sulphydryl-reactive compound that inhibits agonist and antagonist binding to G-protein-coupled receptors that inhibits a variety of GPCRs including adenosine, opioid, muscarinic, adrenergic and dopaminergic receptors IC50 values of 0.1-1.8 μM. Learn MoreStarting at: $115.00
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Chlorisondamine diiodide
Chlorisondamine diiodide is an exceptionally long lasting nicotinic antagonist with IC50 value of ~1.6 mM. Learn MoreStarting at: $99.00
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GBR 12783 dihydrochloride
GBR 12783 dihydrochloride is a potent and selective inhibitor of dopamine uptake with IC50 value of 1.8 nM for inhibition of [3H]-dopamine uptake in rat striatal synaptosomes. Learn MoreStarting at: $99.00
